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http://dx.doi.org/10.1093/occmed/kqn054 | DOI Listing |
Drug Metab Dispos
August 2024
Clinical Pharmacology and Quantitative Pharmacology, BioPharmaceuticals R&D (C.M.), Drug Metabolism and Pharmacokinetics, Oncology R&D (M.W.), Global Medicines Development, Oncology R&D (R.S., D.S.), Integrated Bioanalysis, BioPharmaceuticals R&D (C.B.), and Pharmaceutical Sciences, R&D (R.A.B., M.G.), AstraZeneca, Cambridge, United Kingdom; Drug Metabolism and Pharmacokinetics, Oncology R&D (Z.Z.) and Clinical Pharmacology and Quantitative Pharmacology, BioPharmaceuticals R&D (J.D.), AstraZeneca, Waltham, Massachusetts; Quotient Sciences Ltd, Ruddington, Nottingham, United Kingdom (S.S.); and Clinical Pharmacology and Quantitative Pharmacology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden (M.C.)
J Am Acad Child Adolesc Psychiatry
March 2024
Duke University, Durham, North Carolina.
Objective: A natural experiment that provided income supplements to families has been associated with beneficial outcomes for children that persisted into adulthood. The children in this study are now adults, and many are parents.
Method: The study builds on the longitudinal, representative Great Smoky Mountains study conducted from 1993 to 2020.
Am J Obstet Gynecol MFM
July 2023
UCD Perinatal Research Centre, UCD School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland (Drs Moore, Killeen, Yelverton, Geraghty, and McAuliffe). Electronic address:
Background: The composition of the infant microbiome can have a variety of short- and long-term implications for health. It is unclear if maternal probiotic supplementation in pregnancy can affect the infant gut microbiome.
Objective: This study aimed to investigate if maternal supplementation of a formulation of Bifidobacterium breve 702258 from early pregnancy until 3 months postpartum could transfer to the infant gut.
JAMA Pediatr
October 2022
Emeritus Faculty, Duke University Medical Center, Durham, North Carolina.
Importance: During an ongoing longitudinal cohort study, a casino opening created a natural cash transfer experiment. Some participating families received income supplements, and others did not. The children in this study are now adults.
View Article and Find Full Text PDFJ Am Acad Child Adolesc Psychiatry
August 2022
Jacobs Center for Productive Youth Development, University of Zurich, Switzerland.
Objective: This study tested the "intervention as prevention" hypothesis: that treatment of childhood psychopathology in the community might reduce risk for adult psychopathology.
Method: Analyses were based on a prospective, population-based study of 1,420 children followed up to 8 times during childhood (ages 9-16 years; 6,674 observations) about psychiatric status and specialty mental health services use. Participants were followed up 4 times in adulthood (ages 19, 21, 25, and 30 years; 4,556 observations of 1,336 participants) to assess adult psychopathology.
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