This study developed an objective graphical classification method of spastic diplegic cerebral palsy (CP) gait patterns based on principal component analysis (PCA). Gait analyses of 20 healthy and 20 spastic diplegic CP children were examined to define gait characteristics. PCA was used to reduce the dimensionality of 27 parameters (26 selected kinematics variables and age of the children) for the 40 subjects in order to identify the dominant variability in the data. Fuzzy C-mean cluster analysis was performed plotting the first three principal components, which accounted for 61% of the total variability. Results indicated that only the healthy children formed a distinct cluster; however it was possible to recognise gait patterns in overlapping clusters in children with spastic diplegia. This study demonstrates that it is possible to quantitatively classify gait types in CP using PCA. Graphical classification of gait types could assist in clinical evaluation of the children and serve as a validation of clinical reports as well as aid treatment planning.
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http://dx.doi.org/10.1016/j.gaitpost.2008.06.011 | DOI Listing |
Exp Brain Res
January 2025
School of Rehabilitation Sciences, Université Laval, Quebec, Canada.
Navigating public environments requires adjustments to one's walking patterns to avoid stationary and moving obstacles. It is known that physical inactivity induces alterations in motor capacities, but the impact of inactivity on anticipatory locomotor adjustments (ALA) has not been studied. The purpose of the present exploratory study was to compare ALAs and related muscle co-contraction during a pedestrian circumvention task between active (AA) and inactive young adults (IA).
View Article and Find Full Text PDFJ Neurosci
January 2025
department of radiology, the first hospital of China medical University, Shenyang,110001, China
Hierarchy has been identified as a principle underlying the organization of human brain networks. However, it remains unclear how the network hierarchy is disrupted in Parkinson's disease (PD) motor symptoms and, how it is modulated by the underlying genetic architecture. The aim of this study was to explore alterations in the motor functional hierarchical organization of the cerebrum and their underlying genetic mechanism.
View Article and Find Full Text PDFHum Mov Sci
January 2025
Joint Department of Biomedical Engineering, UNC Chapel Hill & NC State University, Chapel Hill, NC, USA. Electronic address:
Straight line walking currently dominates research into mechanisms associated with walking-related instability; however, the dynamics of everyday walking behavior are far more complex. The figure-8 walk test (F8W) is a clinically-feasible activity that focuses on turning mobility and provides a convenient and relevant task for understanding age-related differences in walking beyond our present knowledge of steady-state behavior. Our purpose was to investigate the effects of age (n = 30 older versus n = 31 younger adults) on path characteristics and the "smoothness" of turning mobility - herein measured via normalized center of mass jerk - during the F8W.
View Article and Find Full Text PDFCureus
January 2025
Department of Research, Department of Regenerative Medicine, Rinaldi Fontani Foundation, Florence, ITA.
An 88-year-old woman presented with a longstanding history of dizziness, tremors, and progressive mental and physical decline, significantly impairing her mobility and autonomy. Recently discharged from an ICU, the patient required extensive support for daily activities. Diagnostic evaluations, including EEG and analysis, revealed irregular frequency peaks and altered cortical activity, particularly in the frontal and prefrontal regions.
View Article and Find Full Text PDFArch Rehabil Res Clin Transl
December 2024
Research Centre Healthy and Sustainable Living, Research group Lifestyle and Health, Utrecht University of Applied Sciences, Utrecht, The Netherlands.
Objective: To evaluate psychometrics of wearable devices measuring physical activity (PA) in ambulant children with gait abnormalities due to neuromuscular conditions.
Data Sources: We searched PubMed, Embase, PsycINFO, CINAHL, and SPORTDiscus in March 2023.
Study Selection: We included studies if (1) participants were ambulatory children (2-19y) with gait abnormalities, (2) reliability and validity were analyzed, and (3) peer-reviewed studies in the English language and full-text were available.
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