[A cause of intracerebral calcifications that should be known: pseudohypoparathyroidism Ib].

Arch Pediatr

Service de pédiatrie, hôpital l'Archet II, route Saint-Antoine-de-Ginestière, 06200 Nice, France.

Published: September 2008

In children, pseudohypoparathyroidism (PHP) is a rare but classical cause of basal ganglia calcifications. It is caused by resistance to parathormone (PTH). Hypocalcemia, which may be symptomatic, is its main feature. We report the case of a 13-year-old boy, affected by type Ib PHP revealed by hypocalcemia and seizures, with basal ganglia calcifications on the CT scan. We describe the characteristics of the 2 main types of PHP and emphasize the search for this disease when basal ganglia calcifications are discovered, even fortuitously, on a cerebral CT scan.

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http://dx.doi.org/10.1016/j.arcped.2008.06.016DOI Listing

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