Objective: Cervical transforaminal epidural steroid injection (TFESI) has become a common treatment for cervical radiculopathy. We describe a case of spinal cord injury caused by direct injection of iohexol into the cervical spinal cord during cervical TFESI.
Case Report: A 55-year-old male suffered from intractable pain in the neck, radiating to his left arm. After undergoing C6-7 TFESI under fluoroscopic guidance, the patient reported a shooting pain during needle insertion, and developed quadriparesis shortly after contrast injection. The radiological findings of the contrast medium and air bubble within the cord indicated needle penetration and intracord contrast injection. The paresis of his right arm and both legs recovered within 4 hours after the procedure. At 1-month follow-up, his left arm paresis had continued to improve. One year after the event, the motor paresis improved except for grasping with the left hand, resulting in a claw hand deformity.
Conclusions: This case report draws attention to this very serious complication of cervical TFESI. It is essential to confirm final needle position using both anteroposterior and lateral fluoroscopy before any injection through the needle.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.rapm.2007.12.006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identification and functional characterization of T-cell exhaustion-associated lncRNA AL031775.1 in osteosarcoma: a novel therapeutic target.
Front Immunol
March 2025
Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Background: Osteosarcoma, an aggressive bone malignancy predominantly affecting children and adolescents, presents significant therapeutic challenges with a 5-year survival rate below 30% in metastatic cases. T-cell exhaustion, characterized by the overexpression of immune checkpoint molecules, contributes to osteosarcoma progression and immune evasion. Although targeting these inhibitory pathways has shown potential in restoring T-cell activity, the molecular regulators of T-cell depletion in osteosarcoma are poorly understood.
View Article and Find Full Text PDFClinical characteristics of varicella-zoster virus central nervous system infection in 108 unimmunocompromised patients.
Front Neurol
February 2025
Department of Neurology, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, China.
Background: Varicella-zoster virus (VZV) central nervous system infection is typically observed in immunocompromised patients, and there is a lack of studies involving large samples of non-immunocompromised individuals. In this study, we retrospectively analyzed 108 non-immunocompromised patients diagnosed with VZV central nervous system infection.
Methods: This retrospective study was conducted in the Department of Neurology, Affiliated Nanjing Brain Hospital, Nanjing Medical University, China.
Editorial: Current methods for detecting and diagnosing stem cell pathogenesis: a focus on translational interventions in the contemporary disease and technology landscape.
Front Cell Dev Biol
February 2025
Wayne State University, Detroit, MI, United States.
A review of cerebrospinal fluid circulation with respect to Chiari-like malformation and syringomyelia in brachycephalic dogs.
Fluids Barriers CNS
March 2025
School of Veterinary Medicine, University of Surrey, Guildford, GU2 7XH, UK.
Cerebrospinal fluid (CSF) plays a crucial role in maintaining brain homeostasis by facilitating the clearance of metabolic waste and regulating intracranial pressure. Dysregulation of CSF flow can lead to conditions like syringomyelia, and hydrocephalus. This review details the anatomy of CSF flow, examining its contribution to waste clearance within the brain and spinal cord.
View Article and Find Full Text PDFFidgetin-like 2 knockdown increases acute neuroinflammation and improves recovery in a rat model of spinal cord injury.
J Neuroinflammation
March 2025
Neuroscience Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Spinal cord injury (SCI) can cause permanent dysfunction proceeding from multifaceted neuroinflammatory processes that contribute to damage and repair. Fidgetin-like 2 (FL2), a microtubule-severing enzyme that negatively regulates axon growth, microglial functions, and wound healing, has emerged as a potential therapeutic target for central nervous system injuries and neuroinflammation. To test the hypothesis that FL2 knockdown increases acute neuroinflammation and improves recovery after SCI, we examined the effects of nanoparticle-encapsulated FL2 siRNA treatment after a moderate contusion SCI in rats.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!