AI Article Synopsis
- - The study aimed to evaluate right ventricular function in Boxers with arrhythmogenic right ventricular cardiomyopathy (ARVC) by using an index of myocardial performance (IMP) and comparing it to a control group of healthy Boxers.
- - Researchers analyzed data from 22 dogs, with half diagnosed with ARVC based on high levels of ventricular premature complexes (VPCs), looking at various cardiac parameters like preejection period and ejection time.
- - The results showed no significant differences in right ventricular performance between ARVC-affected dogs and controls, suggesting that right ventricular dysfunction might not occur in the early stages of ARVC in Boxers, indicating a need for further research using more sensitive methods.
Article Abstract
Objective: To use an index of myocardial performance (IMP) to assess right ventricular function in Boxers with arrhythmogenic right ventricular cardiomyopathy (ARVC).
Animals: 22 Boxers (12 Boxers with ARVC diagnosed by the detection of > or = 1,000 ventricular premature complexes (VPCs)/24 h and 10 Boxers with < or = 5 VPCs/24 h (control dogs). Procedures-Pulsed-wave Doppler recordings of tricuspid inflow and pulmonic outflow were acquired. Preejection period (PEP), ejection time (ET), PEP/ET, and IMP were determined for the right ventricle by use of data from separate cardiac cycles.
Results: A significant difference was not identified between groups for right ventricular PEP, right ventricular ET, right ventricular PEP/ET, or right ventricular IMP. Right ventricular IMP was not significantly correlated with VPC number (r = 0.21) or VPC grade (r = -0.3) in Boxers with ARVC.
Conclusions And Clinical Relevance: Boxers with ARVC did not have significant differences in right ventricular IMP, compared with results for control Boxers. This would suggest that right ventricular dysfunction does not develop in Boxers with ARVC or that a more severe phenotype of the disease may be necessary for detection of dysfunction. Additional studies that use more sensitive techniques to evaluate myocardial function may be warranted.
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| http://dx.doi.org/10.2460/ajvr.69.8.1029 | DOI Listing |
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