Purpose: To determine the demographic factors associated with central corneal thickness (CCT) in Northwestern American Indians/Alaskan Natives (AI/ANs) and to compare these CCT measurements with those of White and African-American persons.
Design: Cross-sectional comparative, observational study.
Methods: We performed ultrasonic pachymetry (DGH-500 Pachette; DGH Technologies, Exton, Pennsylvania, USA) on a random sample of AI/AN subjects from three randomly selected AI/AN tribes in the Northwest United States (n = 429). Pachymetry also was performed on a convenience sample of White (n = 46) and African-American (n = 33) persons. Our main outcome measure was the average of right and left eye CCT.
Results: Average AI/AN CCT was 554.8 +/- 33.9 microm. AI/AN CCT was found to be thicker than that of African Americans (528.5 +/- 33.2 microm) but similar to that of White persons (551.9 +/- 28.3 microm). CCT was greater in AI/AN females than in AI/AN males (557.6 +/- 33.3 microm vs 550.1 +/- 34.5 microm; P = .03). We found no difference in CCT based on percent AI/AN heritage, age, and keratometry readings. We found no significant differences in mean CCT between AI/ANs with glaucoma (556.2 microm) and those who did not have glaucoma (556.6 microm).
Conclusions: CCT measurements for the Northwest AI/AN population are similar to those of White persons but thicker than those of African-American persons. Although glaucoma is common in AI/ANs, we did not find an association with thin CCT. We need future studies to explore the risk factors for glaucoma in AI/ANs.
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http://dx.doi.org/10.1016/j.ajo.2008.05.047 | DOI Listing |
JAMA Netw Open
December 2024
School of Pharmacy, University of Maryland, Baltimore.
Importance: Initiating effective therapy early is associated with improved survival among patients hospitalized with gram-negative bloodstream infections; furthermore, providing early phenotype-desirable antimicrobial therapy (PDAT; defined as receipt of a β-lactam antibiotic with the narrowest spectrum of activity to effectively treat the pathogen's phenotype) is crucial for antimicrobial stewardship. However, the timing of targeted therapy among patients hospitalized with gram-negative bloodstream infections is not well understood.
Objective: To compare the clinical outcomes between patients who were hospitalized with Enterobacterales bloodstream infections receiving early vs delayed PDAT.
Arch Phys Med Rehabil
December 2024
Department of Psychology, Illinois Institute of Technology, Chicago, IL, USA.
Objective: To examine the correlations between individual characteristics among clients with stroke within public vocational rehabilitation (VR) and the employment outcome, as well as the utilization of VR services and their employment outcomes after VR services.
Design: Observational cohort study SETTING: Nationwide vocational rehabilitation data from the Rehabilitation Service Administration Case Service Report (RSA-911) for fiscal year 2022.
Participants: Individuals with stroke as primary cause of disability MAIN OUTCOME MEASURES: employment status and VR service types RESULTS: Of those with stroke who received VR services (n = 1,793), 653 (36.
J Cancer Educ
December 2024
Department of Public Health Sciences, Clemson University, 513 Edwards Hall, Clemson, SC, 29634, USA.
Despite landmark breakthroughs in cancer research, African American adults (AA) bear the highest cancer burden compared to other racial groups in the United States (US). AA adults have twice the likelihood of dying from prostate and uterine cancers compared to White adults, suggesting that there are fundamental issues yet to be addressed when developing and implementing cancer-preventative programs for AA communities. Community-based participatory research (CBPR) empowers community members to identify and prioritize their health problems and preferred strategies to tackle these issues.
View Article and Find Full Text PDFWomens Health (Lond)
December 2024
Division of Infectious Diseases and Global Public Health, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, USA.
Black women in the United States are disproportionately affected by human immunodeficiency virus (HIV) and are less likely to be represented among HIV clinical research participants relative to their cumulative HIV burden. Likewise, Black women are underrepresented in large federally funded HIV research portfolios. Extensive research has demonstrated that Black applicants and women applicants are less likely to receive R01 level funding from the National Institutes of Health, among all applicants.
View Article and Find Full Text PDFJ Med Virol
December 2024
School of Psychology, University of Ottawa, Ottawa, Ontario, Canada.
Racialized and Indigenous communities have been disproportionately affected by COVID-19 infections and mortality, driven by systemic socioeconomic inequalities. However, how these factors specifically influence COVID-19 vaccine uptake is not documented among racialized individuals in Canada. The present study aims to examine COVID-19 vaccine uptake rates and related factors among racialized and Indigenous communities compared to White people in Canada.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!