Highly diastereoselective and enantioselective formal [4 + 1] ylide annulation for the synthesis of optically active dihydrofurans.

J Org Chem

State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Orangic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China.

Published: September 2008

AI Article Synopsis

  • Researchers developed a method to create optically active dihydrofurans using a reaction involving camphor-derived sulfur ylide.
  • The process is highly efficient, meaning it works well in producing the desired compound without wasting resources.
  • The selectivity of the synthesis indicates that the method reliably produces a specific type of dihydrofuran, which is important for achieving the desired chemical properties.

Article Abstract

On the basis of the reactions of camphor-derived sulfur ylide with alpha-ylidene-beta-diketones, highly efficient and selective synthesis of optically active dihydrofurans has been achieved.

Download full-text PDF

Source
http://dx.doi.org/10.1021/jo801135jDOI Listing

Publication Analysis

Top Keywords

synthesis optically
8
optically active
8
active dihydrofurans
8
highly diastereoselective
4
diastereoselective enantioselective
4
enantioselective formal
4
formal ylide
4
ylide annulation
4
annulation synthesis
4
dihydrofurans basis
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!