Cyanopeptoline CB071: a cyclic depsipeptide isolated from the freshwater cyanobacterium Aphanocapsa sp.

Chem Pharm Bull (Tokyo)

Center for Marine Natural Products and Drug Discovery, School of Earth and Environmental Sciences, Seoul National University, Seoul, Korea.

Published: August 2008

Cyanopeptolin CB071 (1), a trypsin inhibitor, was isolated from the freshwater cyanobacterium Aphanocapsa sp. Its complete structure was determined by detailed NMR spectroscopy and MS analyses, along with chemical reactions. The compound showed inhibition of trypsin at a concentration of IC50=2.5 microM.

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Source
http://dx.doi.org/10.1248/cpb.56.1191DOI Listing

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