The new-born mice of the first generation have been examined for changes in morphometric indices after the influence of fopurine, cyclophosphamide and cadmium chloride on their fathers. It is shown that fopurine and cyclophosphamide, the mutagens for mammals, increase the variability of morphometric indices. The method to calculate the morphometric indices of mice may be used for evaluating genetic risk of the compounds for man.
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Trop Biomed
December 2024
Farhat Abbes University, Department of Biochemistry, Biochemistry Laboratory, Setif, Algeria.
In light of the adverse effects of chemical insecticides on the environment and human health, as well as the development of mosquito resistance to them, this study explores the potential of methanol and aqueous flower extracts from Lavandula dentata and Nerium oleander as bioinsecticides against Culiseta longiareolata mosquitoes. Additionally, it aims to assess the impact of these extracts on enzymatic biomarkers and biochemical composition of fourth instar larvae of Culiseta longiareolata.Qualitative analysis revealed the presence of flavonoids, terpenes, gallic and catechic tannins in both plant extracts.
View Article and Find Full Text PDFComput Biol Med
January 2025
Department of Mechanical Engineering, Isfahan University of Technology, Isfahan, Iran. Electronic address:
Atherogenesis is prone in medium and large-sized vessels, such as the aorta and coronary arteries, where hemodynamic stress is critical. Low and oscillatory wall shear stress contributes significantly to endothelial dysfunction and inflammation. Murray's law minimizes energy expenditure in vascular networks and applies to small arteries.
View Article and Find Full Text PDFThe current study aimed to objectively evaluate the fit of a rectangular, tapered stem to the severely dysplastic hips on the basis of the proximal femoral anatomy and the dimensional properties of the stem. It was hypothesized that the stem size planned with accordance to the diaphyseal canal width alone can accommodate the distal femur successfully with no sizing mismatch. Forty-six patients (53 hips) suffering from secondary osteoarthritis due to hip dysplasia scheduled for total hip arthroplasty (THA) with a subtrochanteric transverse shortening osteotomy were included.
View Article and Find Full Text PDFActa Bioeng Biomech
September 2024
Laboratory of Physiotherapy and Physioprevention, Institute of Physiotherapy and Health Sciences, Academy of Physical Education, Katowice, Poland.
: The main aim of this paper was to perform the morphological assessment of children's mandibles of different etiology of dys-functions within the temporomandibular joint, from isolated idiopathic ankylosis to craniofacial malformations co-existing with genetic disorders. : The investigations encompassed seven patients at the age of 0-3. Measurements were conducted on the basis of data obtained from computed tomography.
View Article and Find Full Text PDFCardiovasc Toxicol
January 2025
Department of Morphological Sciences, State University of Maringa, Maringa, Parana, Brazil.
5-Fluorouracil (5-FU) is a chemotherapeutic that is used to treat solid tumors. However, 5-FU is associated with several side effects, including cardiotoxicity. Considering the importance of the intrinsic cardiac nervous system (ICNS) for the heart and that little is known about effects of 5-FU on this nervous system plexus, the purpose of the present study was to evaluate effects 5-FU at a low dose on the ICNS and oxidative and inflammatory effects in the heart in Wistar rats.
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