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: An alternative host for fungal pathogens attacking cultivated barley.
Plant Dis
March 2025
University of Minnesota, Plant Pathology, 1991 Upper Buford Cir., 495 Borlaug Hall, St. Paul, Minnesota, United States, 55108;
Wild grasses can serve as hosts for plant pathogens that attack small grain cereal crops, thereby perpetuating the disease cycle and potentially initiating epidemics. Foxtail barley () is a perennial grass species that is common across North America and can often be found growing near cultivated barley fields. Despite the close proximity of the two plant species in agro-ecosystems, few studies have been advanced to characterize the compatibility of to barley pathogens and its possible role in disease epidemiology.
View Article and Find Full Text PDFAntibiotic chemoprophylaxis for close contacts of invasive group A streptococcus in community settings: evidence review.
J Infect
March 2025
UK Health Security Agency, Field Services North West, Liverpool, L1 3DS. Electronic address:
Objectives: Revised UK guidelines for the management of contacts of invasive group A Streptococcus (iGAS) infection in community settings were published in December 2022. We present the findings of a narrative review which informed the public health recommendations around the provision of antibiotic chemoprophylaxis detailed in the updated guidelines.
Methods: We conducted a literature review of studies reporting the risk of iGAS infection associated with specific risk factors.
Candida glabrata subverts intracellular trafficking and modulates autophagy to replicate in human epithelial cells.
Microb Pathog
March 2025
Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Department of Microbiology, México City, México. Electronic address:
In recent years, Candida glabrata (C. glabrata) has emerged as a pathogen responsible for systemic mortal infections. C.
View Article and Find Full Text PDFDuration of systemic antifungal therapy for patients with invasive fungal diseases: A reassessment.
Mol Aspects Med
March 2025
Department of Infectious Diseases and Tropical Medicine, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique -Hôpitaux de Paris, Université de Paris Cité, Paris, France; Institut Pasteur, Centre d'Infectiologie Necker-Pasteur, National Reference Center for Invasive Mycoses and Antifungals, France. Electronic address:
Invasive fungal diseases are associated with significant morbidity and mortality, especially among immunocompromised patients, and often prompt for rapid and aggressive treatment aiming cure. Due to the expanding magnitude of patients burdened by chronic immunosuppression and affected by fungal diseases, the diversity of clinical settings has risen. This often results in prolonged therapy (induction, consolidation and maintenance) associated with potentially severe side effects, and clinicians face the challenging decisions of when and how to stop anti-fungal therapy.
View Article and Find Full Text PDFGene sequencing of 16S, 18S, and ITS regions is a crucial tool in molecular diagnostics, especially in microbiology, pathology and forensic medicine. These genes contain conserved and variable regions and are widely used for the taxonomic classification of bacteria and eukaryotes. Sequencing of 16S rDNA helps detect bacterial infections, while sequencing of ITS regions and 18S rDNA is used to identify fungal or parasitic infections, especially when traditional methods are ineffective.
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