Gastric infiltration of diffuse large B-cell lymphoma: endoscopic diagnosis and improvement of lesions after chemotherapy.

World J Gastroenterol

Department of Gastrointestinal Endoscopy, Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran", Vasco de Quiroga 15, Tlalpan 14000, Mexico City, Mexico.

Published: July 2008

Diffuse large B-cell lymphoma (DLBCL) is the most common histologic subtype of the non-Hodgkin's lymphoma (NHL) accounting for about 40% of all NHLs. This is a case report about the endoscopic appearance of a DLBCL with infiltration to the stomach in a 39-year-old female. She had a 6-mo history of lumbar and left upper quadrant pain with intermittent episodes of melena. A computer tomograghy (CT) scan showed mural thickening of the gastric antrum. Endoscopic examination revealed multiple gastric ulcers. Definite diagnosis could be made by endoscopic biopsies and the patient had a good response to chemotherapy. This response correlated well with a further endoscopic follow-up. A follow-up endoscopic examination could be considered to evaluate a good response to chemotherapy in DLBCL patients with secondary gastric dissemination.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731198PMC
http://dx.doi.org/10.3748/wjg.14.4407DOI Listing

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