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Activin A promoted the anti-tumor effect of ActRIIA CD8 T cells in mouse hepatoma.
Cancer Med
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Department of Clinical Laboratory, Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Background: Activin A, a noteworthy member of the TGF-β superfamily. Activin A can regulate the biological functions of various immune cells, such as macrophages, neutrophils, NK cells, etc. The purpose of this study is to investigate the regulatory effect and related mechanisms of activin A on CD8 T cells.
View Article and Find Full Text PDFCryoablation plus chemotherapy regimen enhance anti-tumor immune response in a mouse model of Lewis lung cancer.
Int J Hyperthermia
December 2024
Oncology Department, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Background: Cryoablation (cryo) is a local anti-tumor method and activation of immunity is one of its mechanisms, but it is affected by many factors. Numerous studies have proved that combination therapy based on cryo can activate immunity more effectively and synergistically. Cryo combined with chemotherapy(chemo) has been proven to improve the quality of life and prolong survival of tumor patients, but the immune effect is still unclear.
View Article and Find Full Text PDFVaccine protection of broilers against various doses of wild-type Typhimurium and changes in gut microbiota.
Vet Q
December 2025
School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, Australia.
This study evaluated the impact of vaccine diluents (peptone or water) on the protective effects of Typhimurium (. Typhimurium) vaccine. Vaccinated broilers were challenged with different doses of wild-type .
View Article and Find Full Text PDFEffects of a laminarin-rich algal extract on caecal microbiota composition, leukocyte counts, parasite specific immune responses and growth rate during Eimeria tenella infection of broiler chickens.
Vet Parasitol
December 2024
Department of Microbiology, Swedish Veterinary Agency, Uppsala SE 751 89, Sweden.
Coccidiosis, infection with protozoan parasites of genus Eimeria, is a major problem in poultry husbandry world-wide. The disease is currently managed by coccidiostats and live vaccines, but these approaches are not sustainable. Hence, it is important to identify new means to control the infection and/or ameliorate its detrimental effects on gut health.
View Article and Find Full Text PDFImmunomodulatory Acidic Polysaccharide from Jujube Fruit ( Mill.): Insight into Their Chemical Characteristics and Modes of Action.
J Agric Food Chem
December 2024
Department of Pharmacy, the First Hospital of China Medical University, Shenyang City 110001, China.
Jujube ( Mill.) has been consumed globally as a fruit and a nutraceutical food for millennia. This study presents the isolation and purification of a novel water-soluble polysaccharide fraction, ZJMP-2, from Mill.
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