Target-selective degradation of proteins by porphyrins upon visible photo-irradiation.

Chem Commun (Camb)

Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.

Published: August 2008

A porphyrin derivative effectively and selectively degraded the target transcription factor, human estrogen receptor-alpha (hER-alpha), upon visible light irradiation, in the absence of additives and under neutral conditions.

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http://dx.doi.org/10.1039/b806961aDOI Listing

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