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Ovarian Masses in Children: Surgical Experience and Outcomes.
J Indian Assoc Pediatr Surg
November 2024
Department of Pediatric Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Aims: This study aims to review our experience of treating ovarian masses in children with an emphasis on clinical presentation, diagnosis, treatment, and outcome.
Methods: We retrospectively reviewed the electronic medical records of all patients below 18 years of age who underwent surgical treatment for ovarian masses at our institute between 2009 and 2023. Study variables included demography, clinical presentation, physical findings, tumor markers, radiologic features, operative details, histopathology, follow-up status, and overall survival.
Virilization, Ovarian Hyperthecosis, and Torsion Masquerading as Malignancy: A Case Report.
J Pediatr Adolesc Gynecol
December 2024
Department of Surgery, Division of Pediatric and Adolescent Gynecology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address:
Background: Premenopausal females with signs of androgen excess and oligomenorrhea are commonly evaluated for polycystic ovarian syndrome or for an androgen-secreting tumor if a pelvic mass is present. Ovarian hyperthecosis (OHT) as a cause of these symptoms in adolescents is rare.
Case: A 15 year-old female with primary amenorrhea and signs of virilization was referred to Pediatric and Adolescent Gynecology after pelvic imaging demonstrated a pelvic mass, suspected to be arising from the right ovary, and an adjacent paratubal cyst.
Ovarian Hyperstimulation and Maternal Virilisation with Successful Pregnancy Outcome: A case report.
Sultan Qaboos Univ Med J
November 2024
Radiology, The Royal Hospital, Muscat, Oman.
Hyperreactio luteinalis (HL) and ovarian hyperstimulation syndrome during pregnancy are both benign conditions where the ovaries are enlarged with presence of multiple thin-walled cysts. The differential diagnosis is ovarian malignancy. Hyperandrogenism with resultant maternal virilisation could be seen in some cases of HL as well as in androgen secreting tumours.
View Article and Find Full Text PDFDiagnostic pitfalls in ovarian androgen-secreting tumors in postmenopausal women with rapidly progressed severe hyperandrogenism.
Post Reprod Health
November 2024
Obstetrics and Gynecology Unit, ASST Santi Paolo e Carlo, San Paolo University Hospital, Milan, Italy.
Article Synopsis
- The study discusses two rare cases of postmenopausal women experiencing rapid virilization and high testosterone levels, despite negative imaging results for ovarian masses.
- Both patients underwent hormone profiling and inconclusive imaging, leading to a suspicion of ovarian tumors, prompting surgical intervention through laparoscopic oophorectomy.
- Histological examination after surgery confirmed Leydig cell tumors in one patient and thecoma in the other, with testosterone levels normalizing and symptoms improving post-surgery, emphasizing the need for thorough evaluation of androgen excess in postmenopausal women.
Pure Leydig cell tumor of the ovary: a rare presentation of a rare entity in a pregnant patient.
Future Sci OA
December 2024
Pathology department, King Abdullah University Hospital, Jordan university of science and technology, Irbid, Jordan.
Leydig cell tumors (LCT) are rare neoplasms that represent less than 0.1% of all ovarian tumors. This tumor usually presents with signs and symptoms of excess androgen levels.
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