AI Article Synopsis
- The study examines how malignant tumors invade surrounding tissues, specifically how cancer cells penetrate the basal lamina and interact with connective tissue.
- It highlights the alterations in the collagen matrix during breast cancer progression and how these changes may influence cancer development.
- The review will also investigate how different types of collagen affect the behavior of breast cancer cells and their molecular changes.
Article Abstract
During the invasive phase of malignant tumors, neoplastic cells break into the basal lamina and enter in contact with the underlying connective tissue, which concurrently undergoes extensive modifications. The aim of our present minireview is to focus the changes in the collagenous matrix occurring during breast cancer progression and to explore the possible effects of different collagen substrates on breast cancer cell behavior and proteomic modulation.
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| http://dx.doi.org/10.1080/03008200802147779 | DOI Listing |
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