Objective: To examine whether Lapprotector, a protective film and ring device for protecting wounds, can prevent wound infection after open appendectomy.
Methods: We performed open appendectomy on 64 patients between 2004 and 2006. In September 2005, we started using Lapprotector to protect the site of incision (McBurney's point). Patients were divided into two groups as follows: Lapp(-), n = 32; Lapp(+), n = 32. Patient demographics were not statistically different and antibiotic protocols were identical.
Results: In the Lapp(-) group, the appendix was perforated in seven patients (21.9%) and not perforated in 25 patients (78.1%). In the Lapp(+) group, the appendix was perforated in nine patients (28.1%) and not perforated in 23 patients (71.9%). For perforated cases, incisional wound infection was seen in three out of seven patients (42.9%) in the Lapp(-) group and in no patient (0%) in the Lapp(+) group, a significant difference (p < 0.05, Chi-squared test). For nonperforated cases, wound infection was seen in only one out of 25 patients (4.0%) in the Lapp(-) group.
Conclusion: We recommend using Lapprotector to prevent incisional wound infection in patients requiring open appendectomy, especially in cases where the appendix is perforated.
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http://dx.doi.org/10.1016/S1015-9584(08)60068-8 | DOI Listing |
Eur J Trauma Emerg Surg
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Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1416634793, Iran; Wound Care Solution, Nano Fanavaran Narin Teb Co., Tehran, P.O. Box 19177-53531, Iran; Physical Chemistry I, Department of Chemistry and Biology & Research Center of Micro and Nanochemistry and Engineering (Cμ), University of Siegen, 57076 Siegen, Germany. Electronic address:
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Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430070, China. Electronic address:
The healing of bacteria-infected wounds has long posed a significant clinical challenge. Traditional hydrogel wound dressings often lack self-healing properties and effective antibacterial characteristics, making wound healing difficult. In this study, a bioactive small molecule cross-linking agent 4-FPBA/Lys/4-FPBA (FLF) composed of 4-formylphenylboronic acid (4-FPBA) and lysine (Lys) was utilized to cross-link guar gum (GG) and a tannic acid/iron (TA/Fe) chelate through multiple dynamic bonds, leading to the formation of a novel self-healing hydrogel dressing GG-FLF/TA/Fe.
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Chryseobacterium indologenes is a rare human pathogen which is nowadays considered an emerging fearsome organism because of its upcoming antibiotic resistance. We present a quite unique case of a multi drug resistant C. indologenes surgical wound infection in a patient submitted to cannulated screw fixation of a displaced medial malleolus fracture.
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