Synthesis and biological evaluation of C-12' substituted vinflunine derivatives.

Bioorg Med Chem Lett

Shanghai Hengrui Pharmaceuticals Co., Ltd., 279 Wenjing Road, Shanghai 200245, China.

Published: August 2008

A series of novel C-12' substituted vinflunine derivatives have been synthesized. Several compounds in this series possess comparable in vitro cytotoxic potency against A549 cell lines.

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Source
http://dx.doi.org/10.1016/j.bmcl.2008.07.025DOI Listing

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