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J Fr Ophtalmol
January 2025
Service d'ophtalmologie, CHU et université de Rennes, 2, rue Henri-le-Guilloux, 35000 Rennes, France.
Ann Cardiol Angeiol (Paris)
November 2024
Service de cardiologie, Centre Hospitalier de Versailles, Hôpital André Mignot, Le Chesnay-Rocquencourt, France. Electronic address:
J Craniomaxillofac Surg
October 2024
U.O. Chirurgia Maxillo-Facciale, Ospedale Sant'Andrea di Roma, Facoltà di medicina e psicologia, Università di Roma "La Sapienza", Italy. Electronic address:
Graves-Basedow's disease (GBD) is an autoimmune pathology that affects the thyroid and is characterized by the presence of goiter, hyperthyroidism, ophthalmopathy, and dermopathy. Graves-Basedow ophthalmopathy (GBO) is a set of inflammatory and infiltrative alterations of the orbital tissue that affects 40-90% of subjects suffering from GBD. Our study aims to investigate the differences in the clinical outcomes of patients treated with two different techniques: the classic open and the more modern endoscopic.
View Article and Find Full Text PDFCancer Radiother
June 2024
Radiation therapy department, centre Georges-François-Leclerc, Dijon, France.
Orbital radiotherapy for Graves' ophthalmopathy is an example of non-oncological radiotherapy. First introduced in the 1930s, this treatment has become widely used since the 1980s with several studies showing proof of both effectiveness and safety: a decrease of soft tissue involvement in 70 to 80% of patients and an improvement of ocular mobility in 30 to 80% of patients. Nowadays, it's one of the second line treatment options recognized by the European Group on Graves' orbitopathy in the management of a moderate to severe and active disease after failure of glucocorticoids.
View Article and Find Full Text PDFEndokrynol Pol
March 2024
Pathophysiology Division, Department of Pathophysiology and Endocrinology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Thyroid orbitopathy (TO) is the most common cause of orbital tissue inflammation, accounting for about 60% of all orbital inflammations. The inflammatory activity and severity of TO should be diagnosed based on personal experience and according to standard diagnostic criteria. Magnetic resonance imaging (MRI) of the orbit is used not only to identify swelling and to differentiate inflammatory active from non-active TO, but also to exclude other pathologies, such as orbital tumours or vascular lesions.
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