Introduction: Excessive alcohol intake can pose a serious problem in public health. The development of instruments to classify the consumers correctly is the first stage in the epidemiologic investigation.
Objective: The internal validity and the reliability was evaluated for a test of problematic alcohol consumption (CP-alcohol) in Bucaramanga, Colombia. 2005--2006. This work provides a measure that is internally consistent and improved reliability of diagnostic technology.
Materials And Methods: Six hundred one subjects between 18 and 60 years participated in the test for CP-alcohol on two occasions. At the same time, a survey on biological variables (VB), socioeconomic (VSE) and dietary (D) was administered. The internal consistency of CP-alcohol was evaluated by calculating the coefficient alpha of Cronbach, and the reliability with coefficients of Spearman and Cohens Kappa. To evaluate the associations among problematic consumption, VB, VSE, D and the risk of alcoholism, the prevalence ratios were calculated using binomial regression.
Results: The frequency of problematic alcohol consumption was of 46.9 (CI 42.9-50.9). Men presented an increased frequency of problematic alcohol use 1.6 times that of women (p<0.001). The coefficient alpha of Cronbach was moderate for all the questions of the test (minimum 0.41, maximum 0.61). In the first application of CP-alcohol, Cronbachs alpha was 0.63, and, in the second, 0.49. Spearmans correlation coefficient was of 0.87 (CI 0.84-0.90) for the population-for men 0.86 (CI 0.82-0.90) and for women 0.86 (CI 0.82-0.90). The Kappas obtained were very good, 0.70 to 0.89. Sex, pleasure provided by alcoholic drinks , risk of alcoholism according to Cut Down on Drinking, Annoyed by Criticism, Guilty Feeling, and Eye Opener (CAGE) and the quantity of consumed alcohol were all correlated with problematic consumption.
Conclusion: CP-alcohol is a useful test for investigating the epidemiology of health problems associated with alcohol use.
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Addiction
January 2025
Alcohol Research Group, Public Health Institute, Emeryville, CA, USA.
Aim: We applied the Institute of Medicine (IOM) definition of racial and ethnic disparities in healthcare to estimate disparities in alcohol-related problems. This estimation involved adjusting for drinking patterns, gender and age, with observed disparities further explained by socioeconomic status (SES). We compared results of five statistical approaches which use different methods for adjusting covariates.
View Article and Find Full Text PDFBMC Med
January 2025
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Background: Since older adults spend significant time in their neighborhood environment, environmental factors such as neighborhood socioeconomic disadvantage, high racial segregation, low healthy food availability, low access to recreation, and minimal social engagement may have adverse effects on cognitive function and increase susceptibility to dementia. DNA methylation, which is associated with neighborhood characteristics as well as cognitive function and white matter hyperintensity (WMH), may act as a mediator between neighborhood characteristics and neurocognitive outcomes.
Methods: In this study, we examined whether DNA methylation in peripheral blood leukocytes mediates the relationship between neighborhood characteristics and cognitive function (N = 542) or WMH (N = 466) in older African American (AA) participants without preliminary evidence of dementia from the Genetic Epidemiology Network of Arteriopathy (GENOA).
J Prev Alzheimers Dis
January 2025
School of Psychology, University of New South Wales, Sydney, NSW 2057, Australia; Neuroscience Research Australia, Margarete Ainsworth Building, 139 Barker St, Randwick NSW 2031, Australia. Electronic address:
Background: A brain healthy lifestyle, consisting of good cardiometabolic health and being cognitively and socially active in midlife, is associated with a lower risk of cognitive decline years later. However, it is unclear whether lifestyle changes over time also affect the risk for mild cognitive impairment (MCI)/dementia, and rate of cognitive decline.
Objectives: To investigate if lifestyle changes over time are associated with incident MCI/dementia risk and rate of cognitive decline.
Clin Gastroenterol Hepatol
January 2025
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:
Hepatocellular carcinoma (HCC) is a major concern for public health. Fatty liver disease, related to alcohol misuse or metabolic syndrome, has become the leading cause of chronic liver disease and HCC. The strong association between type 2 diabetes mellitus and HCC can be partly attributed to the development of metabolic dysfunction associated steatotic liver disease (MASLD).
View Article and Find Full Text PDFJ Clin Epidemiol
January 2025
Department of Health, Medicine and Caring Sciences, Linköping University, Sweden.
Objective: The term 'research participation effects' (RPEs) is intended to capture features and artefacts of study design that may affect measured outcomes in ways that introduce bias into research findings, impacting inference and outcome validity. This systematic review aims to identify which RPEs have been studied in the context of alcohol research and provide an overview of estimates of RPEs on self-reported alcohol consumption.
Study Design And Setting: This systematic review summarises the available evidence on research participation effects in alcohol research.
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