Hypertension has been classified for several years as a "silent killer" because of the lack of associated symptoms. However, hypertension is linked to the development of target organ disease, which leads to cardiovascular and renal disease. Stroke and heart disease rank high in the leading causes of death in the United States and are major contributions to the financial and societal costs in health care. Hypertension is listed as the most common primary diagnosis in America. Therefore, controlling hypertension can be an important factor to reducing the incidence of these prevalent public health concerns. This article highlights the issues of hypertension in women.
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http://dx.doi.org/10.1016/j.ccell.2008.03.011 | DOI Listing |
Ann Surg Oncol
January 2025
Breast Surgery Section, Division of GI and Oncologic Surgery, Massachusetts General Hospital, Boston, MA, USA.
Background: Nipple-sparing mastectomy (NSM) is infrequently performed in older women, at least in part owing to concerns regarding age-related complications. We describe postoperative outcomes of NSM in older women and risk factors for complications, with the goal of informing patient selection and decision-making.
Patients And Methods: Cases of NSM with immediate implant-based reconstruction were identified from an institutional database (2009-2019).
Alzheimers Dement
December 2024
Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Background: Women are at increased risk for Alzheimer's disease (AD) compared to men. Given research supporting up to 40% of AD cases as preventable with lifestyle modification, midlife represents a critical time of life to intervene on dementia risks; however, little research has examined women-specific presentation of risk at midlife, or how menopause staging may impact risk presentation. The aim of this study was to assess dementia risk profiles in women at risk for AD due to family history, including self-reported and lab-based modifiable risks, and to determine the role of menopause on risk presentation.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Biobank for Aging Studies of the University of São Paulo, São Paulo, Brazil.
Background: Previous studies suggest an association between Alzheimer's disease and carotid artery atherosclerosis. However, the association between atherosclerotic carotid plaque composition and Alzheimer's disease pathology (neuritic plaques and neurofibrillary tangles) has not been explored yet.
Method: Carotid arteries were dissected and the segments with the largest obstruction in the carotid bifurcation, and the common and internal carotid arteries were obtained.
Alzheimers Dement
December 2024
Social Science Research Institute, Duke University, Durham, NC, USA.
Background: The Alzheimer's Association reports that more than two-thirds of the approximately 5 million Alzheimer's disease (AD) cases in the USA are women. With studies suggesting a high genetic heritability for AD, gaining a better understanding of the genetic architecture underlying sex disparities in AD and its risk factors could enhance the understanding of their mechanisms.
Method: We conducted genome-wide association studies (GWAS) and pleiotropic meta-analysis of AD and its risk factor-hypertension-in men and women of European ancestry.
Alzheimers Dement
December 2024
Seoul National University, School of Medicine, Seoul, Korea, Republic of (South).
Background: We herein introduce a case that was pathologically confirmed as an advanced stage of LATE.
Method: (case presentation) An 81-year-old woman visited a memory clinic complaining of memory impairment in the past few years. She had no psychiatric history and a history of significant hyperlipidemia and hypertension.
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