Objective: To provide recommendations for the management of postoperative nausea and vomiting (PONV), which may affect as many as 30% of patients. METHODS AND EVIDENCE: Medline, PubMed, and the Cochrane Database were searched for articles published in English from 1995 to 2007. Recognizing that we must work as a team to optimize the care of our patients perioperatively, this guideline was written in partnership with anaesthesiologists.
Options: The areas of clinical practice considered in formulating this guideline are prevention and prophylaxis, treatment, both medical and alternative, and patient education.
Outcomes: Implementation of this guideline should optimize the prevention of and prophylaxis against PONV and the prompt treatment of women who suffer from PONV following gynaecologic surgery. Increased awareness of options for management should help minimize the effects of PONV.
Benefits, Harms, And Costs: PONV results not only in increased patient discomfort and dissatisfaction but also in increased costs related to length of hospital stay. Cost of medications to prevent and treat PONV must be weighed against improved surgical experience for the patient and decreased costs to the system.
Values: Recommendations were made according to the guidelines developed by the Canadian Task Force on Preventive Health Care.
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http://dx.doi.org/10.1016/s1701-2163(16)32895-x | DOI Listing |
S Afr J Surg
December 2024
Department of Biostatistics, Faculty of Health Sciences, University of the Free State, South Africa.
Background: Postoperative patients' risk for developing venous thromboembolism (VTE) can be predicted using the adapted Caprini risk assessment model which informs administration of postoperative VTE prophylaxis. The study aimed to assess the appropriateness of postoperative VTE prophylaxis of patients according to the adapted Caprini scores and investigate whether a patient's HIV status influenced postoperative VTE prophylaxis administration.
Methods: This cohort study included patients who had elective or urgent surgery at a tertiary hospital, Bloemfontein.
Indian J Urol
January 2025
Department of Urology, Christian Medical College Hospital, Vellore, Tamil Nadu, India.
Introduction: Neoadjuvant chemotherapy (NAC) in the management of muscle-invasive bladder carcinoma has not been adopted universally. We studied the oncological outcomes and complications in patients who underwent radical cystectomy (RC) with or without NAC.
Methods: A retrospective review of patients who underwent RC with or without NAC from June 2009 to June 2020 was conducted.
Indian J Urol
January 2025
Department of Urologic Oncology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Introduction: Despite level 1 evidence supporting neoadjuvant chemotherapy (NACT) followed by radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC), its adoption is hindered by concerns about toxicity and detrimental impact on post-RC complications. We retrospectively reviewed post-RC complications at a tertiary care hospital, particularly assessing impact of NACT.
Methods: Data from the institutional bladder cancer database were retrieved for patients aged ≥18 with MIBC (≥American Joint Committee on Cancer Clinical Stage T2), treated with RC between May 2013 and July 2023.
J Clin Orthop Trauma
March 2025
Department of Orthopaedic Surgery, Sengkang General Hospital, Singapore.
Cartilage repair remains a significant challenge due to the tissue's limited innate regenerative capacity. Despite advances in techniques such as microfracture, autologous chondrocyte implantation (ACI), and osteochondral grafting, long-term outcomes are often compromised by complications, including suboptimal tissue integration, graft resorption, and mechanical instability. Recently, biologically augmented scaffold-based cartilage repair has emerged as a promising approach for full-thickness osteochondral lesions.
View Article and Find Full Text PDFJACC Case Rep
January 2025
National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
A 35-year-old man presented to the emergency department with reports of chest pain, progressive shortness of breath, and pedal edema. He had a history of multiple hospital admissions without improvement. Multimodality imaging revealed a suspected giant right atrial myxoma.
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