This article provides an overview of recent contributions to the debate on the ethical use of previously collected biobank samples, as well as a country report about how this issue has been regulated in Spain by means of the new Biomedical Research Act, enacted in the summer of 2007. By contrasting the Spanish legal situation with the wider discourse of international bioethics, we identify and discuss a general trend moving from the traditional requirements of informed consent towards new models more favourable to research in a post-genomic context.
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http://dx.doi.org/10.1111/j.1467-8519.2008.00673.x | DOI Listing |
J Med Internet Res
January 2025
NOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, NOVA University Lisbon, Lisbon, Portugal.
Background: Heart failure (HF) is a significant global health problem, affecting approximately 64.34 million people worldwide. The worsening of HF, also known as HF decompensation, is a major factor behind hospitalizations, contributing to substantial health care costs related to this condition.
View Article and Find Full Text PDFCurr Atheroscler Rep
January 2025
Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, CA, USA.
Purpose Of Review: Discuss the relationship between pregnancy complications and long-term atherosclerotic cardiovascular disease (ASCVD) risk.
Recent Findings: A large body of research confirms an association between pregnancy complications and increased short and long-term ASCVD risk and seeks to understand mechanisms for these associations. Social determinants of health continue to have a critical impact on the prevalence of adverse pregnancy outcomes (APOs) and long term ASCVD risk.
Appl Biochem Biotechnol
January 2025
Department of Neurosurgery, General Medical 300 Hospital, No. 420 Huanghe Road, Guiyang City, 550006, Guizhou Province, China.
Spinal cord injury (SCI) is one of the devastating neurological disorders that leads to a loss of motor and sensory functions. Long non-coding RNA small nucleolar RNA host gene 6 (lncRNA SNHG6) plays a crucial role in inflammatory regulation across various diseases. This study investigates the role of SNHG6 in SCI development and its underlying regulatory mechanisms.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
Research Engineer I, Applied Research Center for Environment & Marine Studies, Research Institute, King Fahd University of Petroleum & Minerals, 31261, Dhahran, Saudi Arabia.
Concerns regarding disinfection byproducts (DBPs) in drinking water persist, with measurements in water treatment plants (WTPs) being relatively easier than those in water distribution systems (WDSs) due to accessibility challenges, especially during adverse weather conditions. Machine learning (ML) models offer improved predictions of DBPs in WDSs. This study developed multiple ML models to predict Trihalomethanes (THMs), Haloacetic Acids (HAAs), Dichloroacetonitrile (DCAN), and N-nitrosodimethylamine (NDMA) in WDSs using data collected over 13 years (2008-2020) from 113 water supply systems (WSS) in Ontario.
View Article and Find Full Text PDFJ Nephrol
January 2025
Department of Nephrology, The First Affiliated Hospital of Sun Yat-sen University, 58Th, Zhongshan Road II, Guangzhou, 510080, People's Republic of China.
Background: Positive anti-ribonucleoprotein antibodies may characterize a subgroup of patients affected by lupus nephritis with mild kidney damage, but little is known about their clinical features and long-term prognosis.
Methods: Patients were retrospectively selected from the lupus nephritis database ( http://ln.medidata.
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