Objective: Although there is considerable speculation that family-based socialization processes influence children's safety and risk behaviors, few studies have addressed this important issue. The present study compared the impact of parent practices and teaching about safety on children's current behaviors and their intended future behaviors when they reach adulthood.
Design And Measures: Children 7 to 12 years of age were interviewed and asked to report on their parents' practices and teachings (discussions, expectations for children's behavior) regarding five common safety behaviors. As well, the children reported on their own current practices and how they intended to behave when an adult. When appropriate, they provided explanations about why their parents engage in fewer safety behaviors than they required of their children.
Results: Children's current behavior was best predicted by parental teaching, however, how children planned to behave when they were adults was best predicted by parents' practices. Children attributed less frequent safety behaviors by their parents than themselves to general attributes of adults and their parent having special skills that made the safety practices less necessary than was true for children.
Conclusion: These results highlight family influences on children's adoption of safety and risk practices and support the notion of intergenerational transmission of risk behaviors.
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http://dx.doi.org/10.1037/0278-6133.27.4.498 | DOI Listing |
JAMA Netw Open
January 2025
Alzheimer Center Limburg, Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Importance: Baseline cerebral microbleeds (CMBs) and APOE ε4 allele copy number are important risk factors for amyloid-related imaging abnormalities in patients with Alzheimer disease (AD) receiving therapies to lower amyloid-β plaque levels.
Objective: To provide prevalence estimates of any, no more than 4, or fewer than 2 CMBs in association with amyloid status, APOE ε4 copy number, and age.
Design, Setting, And Participants: This cross-sectional study used data included in the Amyloid Biomarker Study data pooling initiative (January 1, 2012, to the present [data collection is ongoing]).
In patients with transplant-eligible newly diagnosed multiple myeloma, induction therapy with a quadruplet regimen prior to autologous transplant is the standard of care. The phase III IFM2020-02-MIDAS study (NCT04934475) assessed a minimal residual disease (MRD)-driven consolidation and maintenance strategy following induction with isatuximab, carfilzomib, lenalidomide, and dexamethasone (IsaKRD). Here, we report safety and efficacy outcomes of six 28-day cycles of IsaKRD.
View Article and Find Full Text PDFAnn Hematol
January 2025
Division of Hematology-Oncology, Hanyang University Seoul Hospital, Seoul, Republic of Korea.
Ravulizumab is a second-generation complement component 5 (C5) inhibitor (C5i) approved for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) following positive results from two pivotal trials in patients with PNH originally naive to C5i treatment and eculizumab-experienced patients with PNH. In both trials, after the 26week primary evaluation period, all patients received ravulizumab for up to 6 years. To report ravulizumab treatment outcomes in patients with PNH originally naive to C5i treatment and eculizumab-experienced patients with PNH treated for up to 6 years.
View Article and Find Full Text PDFInt Arch Occup Environ Health
January 2025
Division of Work and Health, Federal Institute for Occupational Safety and Health (BAuA), Nöldnerstr. 40-42, 10317, Berlin, Germany.
Purpose: This study analyzed longitudinal data to examine whether occupational sitting time is associated with increases in body mass index (BMI) and five-year cardiovascular disease (CVD) risk.
Methods: We included 2,000 employed men and women (aged 31-60) from the German Study on Mental Health at Work (S-MGA) for a BMI analysis and 1,635 participants free of CVD at baseline (2011/2012) for a CVD analysis. Occupational sitting time was categorized into five groups (< 5, 5 to < 15, 15 to < 25, 25 to < 35, and ≥ 35 h per week).
Int J Gynaecol Obstet
January 2025
Ariadne Labs at Brigham and Women's Hospital and the Harvard T H Chan School of Public Health, Boston, Massachusetts, USA.
Background: The intrapartum period is critical for reducing maternal and perinatal morbidity and mortality. The WHO's Safe Childbirth Checklist (SCC) was designed as a reminder of the most critical, evidence-based practices (EBPs) to improve quality care and reduce preventable complications and deaths.
Objective: To assess the impact of SCC on birth attendant behavior and maternal and newborn health outcomes.
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