Effect of inhibitors of arachidonic acid conversion in platelets on thrombin-fibrinogen interaction and thrombin tolerance.

Bull Exp Biol Med

Department of Biochemistry, Tyumen Medical Academy, Russian Ministry of Health.

Published: October 2007

Experiments on 200 rats showed that inhibitors of arachidonic acid conversion capable of reducing coagulation activity of platelets decrease the content of markers for thrombin--fibrinogen interaction in the plasma and, therefore, decelerate intravascular blood coagulation and increase thrombin tolerance.

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http://dx.doi.org/10.1007/s10517-007-0368-4DOI Listing

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