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Hydrocephalus as a possible additional contributor to cognitive outcome in survivors of pediatric medulloblastoma. | LitMetric

Objectives: The purpose of the study was to assess the relationship between shunted hydrocephalus and intellectual, memory and academic functioning in a group of survivors of pediatric medulloblastoma.

Methods: Data from measures of cognitive, memory, academic and visual-motor functioning were gathered retrospectively from 35 survivors. Of these survivors, 10 (28.6%) required ventriculoperitoneal-shunt placement for hydrocephalus posttumor resection.

Results: Results revealed that participants with shunted hydrocephalus demonstrated significantly lower IQs, lower nonverbal intellectual functioning, lower academic skills in writing and math, and impairments in visual-motor abilities when compared with those without shunt.

Conclusions: These results highlight the need to explore other variables--in addition to radiation and chemotherapy--as risk factors for neurocognitive impairments in survivors. Furthermore, identification of physiological substrates underlying these deficits is needed.

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http://dx.doi.org/10.1002/pon.1349DOI Listing

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