One new steroid alkaloid, 12beta-hydroxylveratroylzygadenine (1) and four known compounds, verdine (2), jervine (3), veramarine (4), and veratroylzygadenine (5), have been isolated from the roots and rhizomes of Veratrum nigrum L. processed by rice vinegar. Their structures were established through a combined analysis of physicochemical properties and spectroscopic evidence. The assay results revealed that compounds 1, 4, and 5 exhibited cell toxicity against human HL-60 cells with IC50 values 52.67, 52.90, and 56.51 micromol/l, respectively.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/10286020802133266 | DOI Listing |
Publication Analysis
Top Keywords
veratrum nigrum
8
nigrum processed
8
processed rice
8
rice vinegar
8
study chemical
4
chemical constituents
4
constituents veratrum
4
vinegar steroid
4
steroid alkaloid
4
alkaloid 12beta-hydroxylveratroylzygadenine
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!