AI Article Synopsis
- The study aimed to evaluate the effectiveness of ropivacaine with clonidine for pain relief after radical retropubic prostatectomy.
- 86 patients were divided into two groups, with one group receiving a mix of bupivacaine, morphine, and clonidine, while the other received ropivacaine with clonidine.
- Results indicated significant differences in side effects like sedation, itching, and nausea, suggesting that ropivacaine with clonidine is a favorable option for managing postoperative pain in these patients.
Article Abstract
Objective: The aim of this study was to find out if ropivacaine with clonidine can be successfully used after radical retropubic prostatectomy.
Material And Methods: A total of 86 patients were randomized into two groups each consisting of 43 patients. Patients in group 1 received epidural bupivacaine/morphine/clonidine and those in group 2 ropivacaine and clonidine. If necessary analgesic, antiemetic or antihistamine drugs were administered. Pain on a visual analogue scale (VAS), motoric and sensoric disturbances, sedation, itching, nausea and vomiting, hypotension, need of antihistamines, naloxon, antiemetics, ephedrine, and analgesics were also documented.
Results: Differences in sedation, itching, nausea and vomiting, motoric and sensoric disturbances, need of antihistamines, antiemetics, and ketoprofen were significant, the other parameters did not show any significant differences.
Conclusions: We recommend the use of ropivacaine with clonidine in the postoperative pain management after radical retropubic prostatectomy.
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| http://dx.doi.org/10.1007/s00482-008-0704-2 | DOI Listing |
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