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Enzymatic phosphatidylation of thiamin, pantothenic acid, and their derivatives. | LitMetric

Enzymatic phosphatidylation of thiamin, pantothenic acid, and their derivatives.

J Nutr Sci Vitaminol (Tokyo)

Research Institute for Bioresources, Okayama University, Kurashiki, Japan.

Published: June 2008

Phospholipase D from Streptomyces sp. was found to catalyze the transfer reaction of the dipalmitoylphosphatidyl residue from 1,2-dipalmitoyl-3-sn-phosphatidylcholine to thiamin, pantothenic acid, and their derivatives in a biphasic system. The following phosphatidylated compounds were synthesized: 1,2-dipalmitoyl-3-sn-phosphatidylthiamin, 1,2-dipalmitoyl-3-sn-phosphatidylthiamin propyl disulfide, 1,2-dipalmitoyl-3-sn-phosphatidylthiamin tetrahydrofurfuryl disulfide, 1,2-dipalmitoyl-3-sn-phosphatidylpantothenic acid, and 1,2-dipalmitoyl-3-sn-phosphatidyl-pantothenyl ethyl ether.

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Source
http://dx.doi.org/10.3177/jnsv.54.255DOI Listing

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