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Right anterior cingulate cortical volume covaries with respiratory sinus arrhythmia magnitude in combat veterans. | LitMetric

Right anterior cingulate cortical volume covaries with respiratory sinus arrhythmia magnitude in combat veterans.

J Rehabil Res Dev

Dissemination and Training Division, Department of Veterans Affairs (VA) Palo Alto Health Care System, Palo Alto, CA 94304, USA.

Published: March 2009

AI Article Synopsis

  • - The anterior cingulate cortex (ACC) is linked to autonomic regulation, with research indicating its volume may be smaller in individuals with PTSD.
  • - The study analyzed 77 U.S. combat veterans, 40 of whom had PTSD, to see how ACC volume relates to the magnitude of respiratory sinus arrhythmia (RSA) at rest.
  • - It found no difference in RSA between veterans with and without PTSD, and a positive correlation was observed between RSA magnitude and right hemisphere ACC volume, regardless of PTSD status.

Article Abstract

Existing data suggest anterior cingulate cortex (ACC) plays a role in autonomic regulation. In persons with posttraumatic stress disorder (PTSD), autonomic regulation appears impaired and smaller mean ACC volume has been reported. This study examined relationships between ACC volume and the magnitude of respiratory sinus arrhythmia (RSA) in 77 U.S. combat veterans at rest, 40 of whom met criteria for PTSD. RSA magnitude did not differ in combat survivors with and without PTSD, which contradicts studies comparing civilians with PTSD to nontraumatized controls. RSA magnitude was positively correlated with right but not left hemisphere ACC volume. This finding was statistically independent of the presence or absence of PTSD.

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Source
http://dx.doi.org/10.1682/jrrd.2007.06.0082DOI Listing

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