AI Article Synopsis
- Advances in pig gene identification and mapping have led to a genetic linkage map that now contains nearly 3000 loci and is expected to grow with the addition of more genes and markers.
- Recent studies on quantitative trait loci (QTL) have pinpointed significant chromosomal regions related to economically important traits, aiding pigs' production through marker-assisted selection (MAS).
- The ongoing research into gene co-expression and its implications not only benefits the pig industry but also plays a crucial role in human disease studies and xenotransplantation.
Article Abstract
Advances in pig gene identification, mapping and functional analysis have continued to make rapid progress. The porcine genetic linkage map now has nearly 3000 loci, including several hundred genes, and is likely to expand considerably in the next few years, with many more genes and amplified fragment length polymorphism (AFLP) markers being added to the map. The physical genetic map is also growing rapidly and has over 3000 genes and markers. Several recent quantitative trait loci (QTL) scans and candidate gene analyses have identified important chromosomal regions and individual genes associated with traits of economic interest. The commercial pig industry is actively using this information and traditional performance information to improve pig production by marker-assisted selection (MAS). Research to study the co-expression of thousands of genes is now advancing and methods to combine these approaches to aid in gene discovery are under way. The pig's role in xenotransplantation and biomedical research makes the study of its genome important for the study of human disease. This review will briefly describe advances made, directions for future research and the implications for both the pig industry and human health.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447406 | PMC |
| http://dx.doi.org/10.1002/cfg.261 | DOI Listing |
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