We describe a probabilistic peptide fragmentation model for use in protein databank searching and de novo sequencing of electrospray tandem mass spectrometry data. A probabilistic framework for tuning of the model using a range of well-characterized samples are introduced. We present preliminary results of our tuning efforts.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447321 | PMC |
| http://dx.doi.org/10.1002/cfg.370 | DOI Listing |
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