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Protocol for a multicentre, prospective, open-label, randomised controlled trial to compare PROs and safety outcomes between preoperative and postmastectomy radiotherapy in locally advanced breast cancer patients with immediate reconstruction via a deep inferior epigastric perforator flap (CAPPELLA) in China.
BMJ Open
January 2025
Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Introduction: Despite its therapeutic advantages, postmastectomy radiotherapy (PMRT) increases the risk of complications and often leads to poor cosmesis in women undergoing breast reconstruction. Preoperative radiotherapy followed by skin-sparing mastectomy and deep inferior epigastric perforator (DIEP) flap reconstruction is technically feasible, with low rates of surgical complications and good short-term oncological outcomes. Further evaluation in a randomised trial comparing preoperative radiotherapy versus conventional PMRT in breast reconstruction is required to assess both oncological and patient-reported outcomes (PROs).
View Article and Find Full Text PDFCervico-acromial flap for large defects in face and neck reconstruction: 34-year experience.
J Stomatol Oral Maxillofac Surg
January 2025
Department of Facial and Cervical Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.33, Ba Da Chu Road, Shi Jing Shan District, Beijing 100144, China. Electronic address:
Background: Extensive cervicofacial defects often lead to functional and aesthetic impairments. The pre-expanded cervico-acromial flap technique is reliable and cost-effective for addressing such defects.
Objective: To introduce our 34 years' experience on pre-expanded cervico-acromial flap technique, emphasizing key surgical techniques.
Application of pedicled supraclavicular flaps in hypopharyngectomy with preservation of laryngeal function.
BMC Surg
December 2024
Department of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Southwest Medical University, No.25, Taiping Street, Jiangyang District, Luzhou, 646000, China.
Objective: To evaluate the efficacy of pedicled supraclavicular flaps in hypopharyngectomy reconstruction, with a focus on preserving laryngeal function.
Methods: From August 2019 to June 2022, 14 patients with primary hypopharyngeal carcinoma who met the inclusion and exclusion criteria and underwent the repair of hypopharyngeal defects using pedicled supraclavicular flaps were included retrospectively. Relevant clinical evaluation indicators include patient characteristics, defect sizes, flap sizes, flap harvesting time, postoperative hospital stay, postoperative complications, recurrence, and survival outcomes.
Long-Term Follow-Up of Single-Step Free Vascularized Lymph Node Transfer for the Management of Combined Genital and Lower Extremity Lymphedema: A Case Report.
Microsurgery
January 2025
Department of Plastic and Reconstructive Surgery, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
The occurrence of genital lymphedema with lower extremity involvement is rare. There is no standard approach in the management of combined genital and lower extremity lymphedema (CGLL). The limited literature available on the management of CGLL reveals the use of multiple procedures, including vascularized lymph node transfer (VLNT), lymphovenous anastomosis (LVA), and debulking.
View Article and Find Full Text PDFTHE EFFECT OF SUBCUTANEOUS EPINEPHRINE DOSAGE ON BLOOD LOSS IN SURGICAL INCISION.
J Ayub Med Coll Abbottabad
November 2024
Department of Plastic surgery and Reconstruction, Dr. Ruth KM Pfau Civil Hospital Karachi-Pakistan.
Article Synopsis
- This study investigates the effect of different dosages of epinephrine on bleeding during supraclavicular flap surgeries, noting the lack of prior research in this area.
- The trial involved three groups: one receiving a higher concentration of epinephrine (1:200,000), one with a lower concentration (1:400,000), and a control group with saline only.
- Results showed that both epinephrine groups experienced significantly less blood loss compared to the control group, but there was no notable difference in blood loss between the two epinephrine dosages.
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