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Serpiginous-Like Choroiditis with ANCA-PR3 Vasculitis in a Patient from Endemic Country: A Complex Phenotypic, Immunological and Epidemiological Puzzle.
Ocul Immunol Inflamm
December 2024
Division of Infectious Diseases, Integrated Health Services Institute (IHI), Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Purpose: To report a complex case of serpiginous-like choroiditis (SLC) in a patient with anti-neutrophil cytoplasmic antibody (ANCA)-anti-proteinase 3 (PR3)-associated vasculitis with systemic involvement.
Methods: Case report.
Results: A 40-year-old male from a tuberculosis (TB)-endemic region presented with bilateral active SLC lesions.
Candy Cane Hypopyon Secondary to Intraocular Mantle Cell Lymphoma: A Case Report.
Case Rep Ophthalmol
December 2024
The Ocular Immunology and Uveitis Foundation, Waltham, MA, USA.
Introduction: Bilateral hemorrhagic hypopyon, also known as candy cane hypopyon, is an extremely rare presentation which we report as a unique case in association with intraocular mantle cell lymphoma (MCL).
Case Presentation: A 63-year-old white male presented with a 3-week history of conjunctival injection OS that was unresponsive to erythromycin ointment and topical steroids, in the setting of recently discovered diffuse lymphadenopathy and malaise. On presentation, he was found to have bilateral hemorrhagic hypopyon.
Primary Intraocular Lymphoma: Rad-Path and Ophthalmologic Correlation.
AJNR Am J Neuroradiol
September 2024
(1) University of Rochester, School of Medicine and Dentistry, Rochester NY 14620 (D.S), (2) Eastern Virginia Medical School, Norfolk, VA 23507 (J.P), (3) University of Connecticut, School of Medicine, Farmington, CT 06032 (ER), (4) Department of Radiology, Mayo Clinic, Jacksonville, 4500 San Pablo Road, Jacksonville, FL 55902, USA (P.V, A.A, N.S), (5) Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55902, USA (G.B), (6) Department of Pathology, Mayo Clinic, Jacksonville, 4500 San Pablo Road, Jacksonville, FL 55902, USA (S.W).
Primary intraocular lymphoma (PIOL) is a rare form of primary central nervous system lymphoma that poses diagnostic challenges due to its nonspecific clinical features and complex imaging characteristics. This paper presents a focus case and two companion cases, highlighting the complexities in identifying and treating PIOL. In the focus case, A 66-year-old male experienced gradual painless vision loss with choroidal thickening on funduscopic exam and subsequent follow-up MRI.
View Article and Find Full Text PDFComparison of various treatment modalities in patients with primary vitreoretinal lymphoma: A systematic review and meta-analysis.
Clin Exp Ophthalmol
September 2024
School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Background: This systematic review and meta-analysis investigated different treatment modalities' effect on the risk of central nervous system lymphoma progression, ocular disease relapse, systemic lymphoma development and overall survival in primary vitreoretinal lymphoma patients.
Methods: PubMed, EMBASE, Scopus and the Cochrane Library of clinical trials were searched from inception to April 21, 2024. Cohort, cross-sectional and case series studies were included.
Occlusive Vasculitis Following Intravitreal Rituximab Injection for Primary Vitreoretinal Lymphoma.
Ocul Immunol Inflamm
January 2025
Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.
Purpose: We report three cases of occlusive vasculitis following intravitreal rituximab therapy for biopsy-proven primary vitreoretinal lymphoma (PVRL), one of which was following an injection of the biosimilar Riabni (rituximab-arrx, AmGen) and two of which were following an injection of Rituxan (rituximab, Genentech).
Methods: Case series.
Results: Three cases of occlusive vasculitis confirmed with fluorescein angiography are reported 5 days, 8 days, and 3.
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