Objectives: To determine the effectiveness of superselective cavernous artery embolization.
Methods: Eight patients with high-flow priapism were included in this study. All were treated by superselective cavernous artery embolization with microcoils and gelatin sponges. The follow-up examinations consisted of color duplex ultrasonography. The International Index of Erectile Function 5-item questionnaire was used to investigate the patients' erectile function before the onset of priapism, at embolization, and 6 months after embolization.
Results: A unilateral cavernous fistula was found in 7 patients and bilateral fistulas in 1. Of the 8 patients, 2 (1 with unilateral and 1 with bilateral fistulas) initially underwent embolization with a gelatin sponge but presented with recurrence of tumescence 1 week after treatment and required a repeat embolization procedure with microcoils. The other 6 patients (75%) were successfully detumescent after embolization with microcoils. The 6 patients (75%) who underwent embolization with microcoils alone had normal erectile function with a mean International Index of Erectile Function score of 22.20 at 6 months after embolization. The 2 patients (25%) who had required repeat embolization had erectile dysfunction, with a mean International Index of Erectile Function score of 13.00.
Conclusions: Superselective cavernous artery embolization with microcoils is a safe and effective treatment of high-flow priapism. The use of microcoils resulted in greater embolization success and preservation of erectile function, especially in the treatment of a unilateral arterial fistula in a young patient.
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http://dx.doi.org/10.1016/j.urology.2008.01.087 | DOI Listing |
Cureus
January 2025
Department of Physiology, University of Sindh, Jamshoro, PAK.
Background: Erectile dysfunction (ED) in men is overlooked and is often linked with psychogenic causes. Due to cultural barriers, this area of research remains neglected.
Objective: The study was conducted to determine the factors that can be associated with ED in otherwise apparently healthy men.
J Control Release
January 2025
Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; Institute of Urology, Beijing Municipal Health Commission, Beijing 100050, China. Electronic address:
We previously established an effective method to ameliorate erectile dysfunction (ED) using intracavernous injection (ICI) of mesenchymal stem cell (MSC) microspheres. However, the expression of a key neurotrophic factor, brain-derived neurotrophic factor (BDNF), was low in both MSCs and MSC microspheres, restricting the associated neural repair. Based on the hypoxia and oxidative stress microenvironments within cell spheroids and lesion areas, BDNF-expressing nanocomplexes that are dual-responsive to hypoxia and reactive oxygen species were designed to modify MSCs, achieving high BDNF expression in MSC spheroids.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Hepatobiliary Surgery, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang, China.
This study aimed to explore the relationship between the lymphocyte/monocyte ratio (LMR) and erectile dysfunction (ED) in adult men in the United States using a comprehensive dataset. A cross-sectional study design was used to analyze the relationship between the lymphocyte-to-monocyte ratio (LMR) and the prevalence of erectile dysfunction (ED) among adult male participants in the NHANES 2001-2004 dataset. Statistical analyses were performed to adjust for potential confounders and explore non-linear associations, with LMR categorized into quartiles to investigate the relationship with ED prevalence.
View Article and Find Full Text PDFUrogynecology (Phila)
October 2024
Aava Medical Center, Hämeenlinna, Finland.
Importance: Although surgery for pelvic organ prolapse (POP) is generally associated with an improvement in sexual function, knowledge on specific changes is limited.
Objectives: The aim of this study was to describe and compare changes in sexual activity and function during a 5-year follow-up period after POP surgery.
Study Design: This was a nationwide cohort study of 3,515 women operated on for POP in 2015 in Finland.
J Sex Med
January 2025
Department of Urology, Holmesglen Private Hospital, Moorabbin 3189, Victoria, Australia.
Background: The penile suspensory ligament (PSL) plays a significant role in penile support and erection and its injury or congenital absence may result in functional impairment of erectile function.
Aim: To describe the diagnosis and surgical repair technique for PSL abnormalities and overall outcomes.
Methods: A comprehensive review of the literature was performed to understand the anatomic relevance of the PSL and historical management of PSL defects.
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