In this paper, a supervised algorithm for vessel segmentation in red-free images of the human retina is proposed. The algorithm is modular and made up of two fundamental blocks. The optimal values of two algorithm parameters are found out by maximizing proper measures of performances (MOPs) able to evaluate from a quantitative point of view the results provided by the proposed algorithm. The choice of the MOP allows one to tailor the solution to the specific image features to be emphasized. The performances of the algorithm are compared with those of other methods described in the literature. The simulation results show a good trade-off between quality and processing speed times. For instance, in terms of the maximum average accuracy (MAA), K value, and specificity (SP), the best performance outcomes are 0.9587, 0.8069 and 0.9477, respectively.
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http://dx.doi.org/10.1016/j.compbiomed.2008.05.006 | DOI Listing |
Neural Netw
December 2024
CAS Key Laboratory of GIPAS, University of Science and Technology of China, Hefei, China; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China. Electronic address:
In MARL (Multi-Agent Reinforcement Learning), the trial-and-error learning paradigm based on multiple agents requires massive interactions to produce training samples, significantly increasing both the training cost and difficulty. Therefore, enhancing data efficiency is a core issue in MARL. However, in the context of MARL, agent partially observed information leads to a lack of consideration for agent interactions and coordination from an ego perspective under the world model, which becomes the main obstacle to improving the data efficiency of current proposed MARL methods.
View Article and Find Full Text PDFBrief Bioinform
November 2024
Center for Genomics and Biotechnology, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, No. 15 Shangxiadian Road, Cangshan District, Fuzhou 350002, China.
Spatial transcriptomics (ST) technologies enable dissecting the tissue architecture in spatial context. To perceive the global contextual information of gene expression patterns in tissue, the spatial dependence of cells must be fully considered by integrating both local and non-local features by means of spatial-context-aware. However, the current ST integration algorithm ignores for ST dropouts, which impedes the spatial-aware of ST features, resulting in challenges in the accuracy and robustness of microenvironmental heterogeneity detecting, spatial domain clustering, and batch-effects correction.
View Article and Find Full Text PDFTertiary lymphoid structures (TLS) are lymphoid formations that develop in non-lymphoid tissues during chronic inflammation, autoimmune diseases, and cancer. Accurate identification and quantification of TLS in tissue can provide crucial insights into the immune response of several disease processes including antitumor immune response. TLS are defined as aggregates of T cells, B cells and dendritic cells.
View Article and Find Full Text PDFActa Otorhinolaryngol Ital
December 2024
Unit of Audiology, Regional Centre of Cochlear Implants and ENT Diseases, Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro, Italy.
Objectives: This research aims to validate the digits-in-noise (DIN) test for the Italian language and develop a version capable of independently assessing both ears while maintaining acceptable administration times.
Methods: Individual digits from 0 to 9 in Italian were recorded and adjusted to equalise recognition probabilities. An iOS application (APP) was developed for the independent ear test using triplets in noise.
JMIR Form Res
January 2025
Oracle, The Edge Building, Al Falak Street, Dubai Internet City, Dubai, United Arab Emirates, 971 558620820.
Background: Primary health care (PHC) services face operational challenges due to high patient volumes, leading to complex management needs. Patients access services through booked appointments and walk-in visits, with walk-in visits often facing longer waiting times. No-show appointments are significant contributors to inefficiency in PHC operations, which can lead to an estimated 3%-14% revenue loss, disrupt resource allocation, and negatively impact health care quality.
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