AI Article Synopsis
- Cysteine proteinases play a crucial role in various aspects of plant physiology, including development, stress response, and the breakdown of proteins.
- These enzymes are especially noted in the Caricaceae family, where they help protect unripe fruit from physical stress.
- The review suggests that plant cysteine proteinases may function similarly to mammalian proteinases involved in wound healing and also have potential therapeutic applications in areas like digestion and immune response.
Article Abstract
Cysteine proteinases are involved in virtually every aspect of plant physiology and development. They play a role in development, senescence, programmed cell death, storage and mobilization of germinal proteins, and in response to various types of environmental stress. In this review, we focus on a group of plant defensive enzymes occurring in germinal tissue of Caricaceae. These enzymes elicit a protective response in the unripe fruit after physical stress. We propose that these enzymes follow a strategy similar to mammalian serine proteinases involved in blood clotting and wound healing. We show evidence for the pharmacological role of plant cysteine proteinases in mammalian wound healing, immunomodulation, digestive conditions, and neoplastic alterations.
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| http://dx.doi.org/10.1016/j.phytochem.2008.05.016 | DOI Listing |
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