(3aS,4S,6R,6aR)-Tetrahydro-2,2-dimethyl-6-vinyl-3aH-cyclopenta[d][1,3]-dioxol-4-ol, itself available from ribose, provided a convenient entry point for an 18-step preparation of carbocyclic sinefungin. This procedure is adaptable to a number of carbocyclic sinefungin analogs with diversity of heterocyclic base and in the amino acid bearing side chain.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2031829 | PMC |
| http://dx.doi.org/10.1016/j.tetlet.2007.05.079 | DOI Listing |
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