The gastroduodenal ulcer rate and the gastrointestinal hemorrhage occurrence probability after total endoprosthesis of the hip and knee joint were studied. Of 526 patients in 4 (0.7%) after the total joint endoprosthesis operation the gastroduodenal ulcer had occurred, demanding the urgent treatment measures conduction. It is mandatory to conduct an adequate prophylactic measures to the patients, suffering pronounced gastropathy, according to anamnestic data available.

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