A series of azatricyclodiones and octahydro-benzo[f]isoindoles have been synthesized by (4+2) Diels-Alder cycloaddition of maleimides with furfuryl amine. Reaction of azatricyclodiones with isocyanates led to the respective ureides. All of the compounds were screened against a number of bacteria and fungi. One of the compounds (2) displayed moderate antitubercular activity while two compounds (2) and (4) inhibited the fungal growth at 25 μg/mL.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14756360701709383 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Synthesis of azatricyclodiones & octahydro-benzo[f]isoindoles and their antimicrobial evaluation.
J Enzyme Inhib Med Chem
August 2008
Medicinal and Process Chemistry Division Central Drug Research Institute, Lucknow, 226001, India.
A series of azatricyclodiones and octahydro-benzo[f]isoindoles have been synthesized by (4+2) Diels-Alder cycloaddition of maleimides with furfuryl amine. Reaction of azatricyclodiones with isocyanates led to the respective ureides. All of the compounds were screened against a number of bacteria and fungi.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!