The therapeutic potential of embryonic and adult stem cells for skeletal muscle regeneration.

Stem Cell Rev

Department of Developmental Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9133, USA.

Published: September 2008

Muscular dystrophy (MD) refers to a group of more than 30 genetically and clinically heterogeneous disorders, characterized by progressive weakness and degeneration of the skeletal muscles that control movement. To date, MD is still incurable but increasing evidence suggests that stem cells might represent a therapeutic option in the future. This review will outline recent progress in this field involving the use of adult and embryonic stem cells. We will discuss in further detail the nature of these cells and their distinct biological properties which lead to their unique advantages and disadvantages in regard to therapeutic application.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12015-008-9023-3DOI Listing

Publication Analysis

Top Keywords

stem cells
12
therapeutic potential
4
potential embryonic
4
embryonic adult
4
adult stem
4
cells
4
cells skeletal
4
skeletal muscle
4
muscle regeneration
4
regeneration muscular
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!