A study was conducted on the collection of stillbirths occurring during the last 23 years in the Gynaecological Hospital in Bamberg. The data were taken from the birth reports and the recorded course of each pregnancy. The results of the first 22 years were divided into 2 groups, the first 11 years and the subsequent 11 years, to enable better judgement of trend changes. A total number of 354 children died antepartum or subpartum, the larger group (249) being that in the first 11 years of the observation period. The number of stillborn babies decreased from 40 per year (15%) to 3 per year (1.1%) in the first period. In the collective group the regular participation in prenatal visits increased from 24% to 56%. The percentage of single mothers (9%) remained constant. The number of foreign mothers, who are non-German citizens rose from 2% to 8%. As expected, the rate of stillbirths for twins was almost 4 times higher (5.3%) than for the single pregnancies. The percentage of multiparous women decreased from 66% to 48%. The number of stillbirths, preceded by a miscarriage and abortion in the patient's clinical history, remained constant at 17%. The age distribution of the mothers was almost the same for both observation periods. The usual age of the pregnancy at the time of the stillbirth shifted from the 39th-42nd week to the 35th-38th week. The main complication for the entire group was pre-eclampsia, at the rate of 30%. Amnion infection syndrome (4%) and diabetes mellitus (2%) were rare. The primary cause of foetal death was related to placental dysfunction (40%).(ABSTRACT TRUNCATED AT 250 WORDS)
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Arch Toxicol
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Department of Environmental and Molecular Toxicology, Sinnhuber Aquatic Research Laboratory, Oregon State University, Corvallis, OR, 97333, USA.
The constant emergence of new viral pathogens underscores the need for continually evolving, effective antiviral drugs. A key challenge is identifying compounds that are both efficacious and safe, as many candidates fail during development due to unforeseen toxicity. To address this, the embryonic zebrafish morphology, mortality, and behavior (ZBE) screen and the SYSTEMETRIC® Cell Health Screen (CHS) were employed to evaluate the safety of 403 compounds from the Cayman Antiviral Screening Library.
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Multi-Modality Medical Imaging (M3I), TechMed Centre, University of Twente, Technohal 2384,Drienerolaan 5, Enschede, 7522NB, The Netherlands.
Vaginal pessaries have been used for millennia to alleviate symptoms of pelvic organ prolapse (POP). Despite their long-standing use, the success rate of pessary treatment is approximately 60%, and the underlying mechanisms of support are not well understood. This study aims to investigate three previously proposed hypotheses regarding the support mechanisms of pessaries, utilizing supine and upright magnetic resonance imaging (MRI): (1) support by bony structures, (2) support by levator ani muscles (LAM), and (3) the uterus keeping the pessary in place by acting as a lever.
View Article and Find Full Text PDFJ Environ Manage
December 2024
School of Ecology and Nature Conservation, Beijing Forestry University, Beijing 100083, China. Electronic address:
The recovery of community productivity in disturbed temperate forests is affected by fluctuating nutrient environments. How plant growth achieves high biomass accumulation in a limited nutrient environment remains unclear but may be attributed to the flexibility of plant nutrient utilization. Nutrient homeostasis (H) reflects the ability of plant tissues to maintain a relatively constant N and P content under nutrient fluctuations and represents flexible or stable plant nutrient utilization.
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December 2024
Faculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming 650093, China.
Nanomaterials, heralded as the "new materials of the 21st century" for their remarkable physical and chemical properties and broad application potential, have attracted substantial attention in recent years. Among these materials, which challenge traditional physical boundaries, nanodiamonds (NDs) are widely applied across diverse industries due to their exceptional surface multifunctionality and chemical stability. Nevertheless, atomic-level manipulation of NDs presents considerable challenges, which require detailed structural analysis to thoroughly elucidate their properties.
View Article and Find Full Text PDFJ Funct Morphol Kinesiol
December 2024
Department of Experimental and Clinical Medicine, University of Florence, 50134 Firenze, Italy.
Background/objectives: Fine motor movements are essential for daily activities, such as handwriting, and rely heavily on visual information to enhance motor complexity and minimize errors. Tracing tasks provide an ecological method for studying these movements and investigating sensorimotor processes. To date, our understanding of the influence of different quantities of visual information on fine motor control remains incomplete.
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