RNA interference: endogenous siRNAs derived from transposable elements.

Curr Biol

Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh EH9 3JT, UK.

Published: July 2008

The Piwi-interacting RNA interference pathway plays an important role in suppressing transposable elements in the Drosophila germline. Now, deep sequencing of short RNAs from somatic tissue and cell culture has identified a novel class of endogenous siRNAs that may have a similar role in the soma.

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http://dx.doi.org/10.1016/j.cub.2008.05.035DOI Listing

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