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Inter-rater agreement and characterization of pleural line and subpleural fields in canine lung ultrasound: a comparative pilot study between high-frequency linear and curvilinear transducers using B- and M-mode ultrasonographic profiles.
Ultrasound J
January 2025
Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.
Background: Lung ultrasound (LUS) is increasingly utilized in veterinary medicine to assess pulmonary conditions. However, the characterization of pleural line and subpleural fields using different ultrasound transducers, specifically high-frequency linear ultrasound transducers (HFLUT) and curvilinear transducers (CUT), remains underexplored in canine patients. This study aimed to evaluate inter-rater agreement in the characterization of pleural line and subpleural fields using B- and M-mode ultrasonography in dogs with and without respiratory distress.
View Article and Find Full Text PDFPoint-of-Care Lung Ultrasound in Small Animal Emergency and Critical Care Medicine: A Clinical Review.
Animals (Basel)
January 2025
Freelance Veterinarian, 70124 Bari, Italy.
Thoracic point-of-care ultrasound (T-POCUS) has grown in popularity and usage in small animal emergencies and critical care settings due to its non-invasive nature, mobility, and ability to acquire images in real time. This review summarizes current understanding about T-POCUS in dogs and cats with respiratory illnesses, including normal thoracic ultrasonography appearance and numerous pathological situations. The basics of T-POCUS are covered, including equipment, scanning procedures, and picture settings.
View Article and Find Full Text PDFShear stress-induced restoration of pulmonary microvascular endothelial barrier function following ischaemia reperfusion injury requires VEGFR2 signalling.
Am J Physiol Lung Cell Mol Physiol
December 2024
School of Medicine and Conway Institute, University College Dublin, Dublin, Ireland.
Normal shear stress produced by blood flow is sensed by the vascular endothelium and required for maintenance of the homeostatic functions of the endothelium in systemic conduit and resistance vessels. Many critical illnesses are characterised by periods of abnormally reduced or absent shear stress in the lung (e.g.
View Article and Find Full Text PDFA survival case of high-dose amlodipine intoxication with non-cardiogenic pulmonary edema: a case report.
Ann Med Surg (Lond)
November 2024
Venus Hospital, Kathmandu.
Introduction: Dihydropyridines calcium channel blockers at high dose can have conduction abnormalities, reduced inotropism, and non-cardiogenic pulmonary oedema (NCPE) which otherwise, at standard dosage have only vascular selectivity. They remain one of the commonly used anti-hypertensive exhibiting very lethal outcomes (50% mortality rates) in its overdose.
Case Presentation: The authors present a case of a 21-year-old male with amlodipine intoxication with 43 tabs of 10 mg (total of 430 mg) ingestion manifested by loss of consciousness, hypotension, tachycardia, and respiratory distress.
Progress in cytokine research for ARDS: A comprehensive review.
Open Med (Wars)
October 2024
Intensive Care Unit, The Second Affiliated Hospital of Guangxi Medical University, No. 166 Daxuedong Road, Nanning, Guangxi 530007, China.
Article Synopsis
- Acute respiratory distress syndrome (ARDS) is a severe condition marked by lung inflammation and fluid build-up, leading to high mortality rates, often driven by dysregulated cytokine activity.
- This review examines the role of both pro-inflammatory and anti-inflammatory cytokines in ARDS, as well as evaluating potential therapies targeting these cytokines to improve patient outcomes.
- While some therapies targeting cytokines like IL-1 and IL-6 show promise, more comprehensive studies are needed to confirm their effectiveness and develop personalized treatment strategies for ARDS.
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