The conventional methods on making double splints in presurgery of skeletal Class III were complicated. To find an easy method for the improvement of the production of splints and simplify the making process, 17 severe skeletal Class III patients accepted bimaxillary surgery after making double splints were used. According to visual treatment objective (VTO) forecasting on the lateral cephalometric radiograph of ending presurgical orthodontics and analyzing study models, the surgical methods were designed, the mobile osteotomy bone volume was estimated and the maxillary abnormity was classified. For the patients with right midline and without adjusting their occlusion plane, use the single model method (antedisplace maxillary model twice) or double models method (antedisplace maxillary model firstly, and then retrodisplace mandibular model) to make the double splints which guided the fixtion of bimaxillary surgery through their parallel models and simple articulators. The making process of the double splints was simplified and improved, and the postsurgery effects of all patients were satisfied. Therefore, for making the double splints of skeletal Class III bimaxillary surgery, utilizing the proper method on the basis of the specific abnormal conditions of patients can simplify the production process and get twice the result with half the effort.
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Nucleic Acids Res
January 2025
Key Laboratory of Bio-resource and Eco-environment of Ministry of Education, The College of Life Sciences, Sichuan University, 24 South Section 1, 1st Ring Road, Chengdu, Sichuan 610064, P.R. China.
Region-specific RNA modifications are crucial for advancing RNA research and therapeutics, including messenger RNA (mRNA)-based vaccines and immunotherapy. However, the predominant method, synthesizing regionally modified mRNAs with short single-stranded DNA (ssDNA) splints, encounters challenges in ligating long mRNA fragments due to the formation of RNA self-folded complex structures. To address this issue, we developed an efficient strategy using an easily obtained long double-stranded DNA (dsDNA) as a ligation splint after in situ denaturing, while parts of this dsDNA are the templates for transcribing mRNA fragments.
View Article and Find Full Text PDFAm J Phys Med Rehabil
November 2024
PhD, Associate Professor of Physical Therapy, Basic Sciences Department, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Objective: While ultrasound therapy is common for carpal tunnel syndrome, the relative merits of thermal versus pulsed ultrasound remain unclear. This study compares their therapeutic effects.
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J Endod
December 2024
Department of Preventive and Restorative Dentistry, University of Sharjah, College of Dental Medicine, Sharjah, UAE.
This report highlights successful management of a rare case of a mandibular premolar with Oehler's Type IIIb Dens Invaginatus (DI) and peri-invagination periodontitis with guided intentional replantation without root canal treatment. A 22-year-old female patient reported with discomfort and a sinus tract associated with tooth number 21. Clinical examination and cone beam computed tomography revealed tooth number 21 had an Oehler's Type IIIb DI with peri-invagination periodontitis.
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Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, Canada.
Rationale: Adherence to Continuous Positive Airway Pressure (CPAP) for Obstructive Sleep Apnoea (OSA) continues to be low with high termination rates. Alternative therapies to CPAP are needed.
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Cureus
September 2024
Department of Prosthodontics, Crown and Bridge, Sharad Pawar Dental College and Hospital Datta Meghe Institute of Higher Education and Research, Wardha, IND.
The ultimate purpose of a partial prosthetic denture is to protect the rest of the teeth as their discarded functionality is being put back together. A Marburg double crown is a form of retainer that works well by providing splinting action between many abutment teeth as well as retention and support. Compared to traditional clasp-retained removable partial dentures (RPDs), the Marburg double crown transfers load to the abutment teeth's long axis.
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