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Chronic disease management has been a rapidly growing entity in the 21st century as a strategy for managing chronic illnesses in large populations. However, experience has shown that disease management programs have not been able to demonstrate their financial value. The objectives of disease management programs are to create quality benchmarks, such as principles and guidelines, and to establish a uniform set of metrics and a standardized methodology for evaluating them. In order to illuminate the essence of disease management and its components, as well as the complexity and the problematic nature of performing economic calculations of their profitability and value, we collected data from several reports that dealt with the economic intervention of disease management programs. The disease management economic evaluation is composed of a series of steps, including the following major categories: data/information technology, information generation, assessment/recommendations, actionable customer plans, and program assessment/reassessment. We demonstrate the elements necessary for economic analysis. Disease management is one of the most innovative tools in the managed care environment and is still in the process of being defined. Therefore, objectives should include the creation of quality measures, such as principles and guidelines, and the establishment of a uniform set of metrics and a standardized methodology for evaluating them.
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Expert Rev Anticancer Ther
March 2025
Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Introduction: Prostate cancer represents a significant oncological challenge, with its natural history predominantly driven by androgen receptor (AR) signaling. The pivotal role of this pathway underscores the rationale for targeting AR activity in therapeutic strategies. However, the development of resistance mechanisms has highlighted the need for advanced therapies to address the complexity of the castration-resistant status.
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Department of Cardiology, the Third Affiliated Hospital of Qiqihar Medical College, China.
To evaluate the comparative efficacy of Ticagrelor and Clopidogrel in treating patients with coronary heart disease and unstable angina, as well as their effects on serum inflammatory factors, thereby providing a solid foundation for future clinical diagnosis and treatment. The frequency of angina attacks in the Ticagrelor group was lower than in the Clopidogrel group (P<0.05).
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March 2025
Department of Plastic and Cosmetic Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
To compare the drug effects and adverse reactions of doxycycline and isotretinoin in patients with moderate to severe acne. A retrospective analysis was conducted on 98 patients with moderate to severe acne who were treated in the Affiliated Hospital of Nanjing University of Traditional Chinese Medicine from June 2020 to June 2023. They were divided into group A and group B based on actual medication use, with 49 cases in each group.
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March 2025
Department of Nephrology, People's Hospital of Shangrao City, Shangrao, Jiangxi Province, China.
Myeloma nephropathy is a rare but challenging disease. This study aimed to evaluate the efficacy and renal functional outcomes of the VAD chemotherapy regimen and thalidomide treatment for myeloma nephropathy. From August 2022 to December 2023, a total of 94 patients were admitted to People's Hospital of Shangrao City.
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March 2025
Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Hyperkalemia poses significant risks to patients due to its potential to cause life-threatening cardiac and neuromuscular complications. This study aimed to evaluate the effectiveness of different treatment protocols for hyperkalemia in hospitalized patients. This prospective observational study, conducted at Sindh Government Hospital Korangi, Karachi, included adult patients (>18 years) with potassium levels ≥5.
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