Introduction: Promoting appropriate use of drugs is an essential element in achieving quality of health and medical cares for patients and the community, and also to minimize financial burden.
Objective: The objective of this paper is to assess the successful intervention for sustainability and effects in post research phase. To address these problems, a variety of educational, managerial and regulatory strategies to improve prescribing have been tried in Nepal. When training is combined with a managerial intervention i.e. peer-group discussion, it results into improved changes in prescribing practices of paramedics in several practices.
Methodology: A prospective, three-way design study consisting of small group training, small group training followed by peer-group discussion and control was conducted in three regions of Nepal including one hill and two terai (plains) districts from each region. The study included all health post from the sampled districts, making 80 health posts the study population.
Results: The study revealed the effectiveness of the peer-group discussion approach in improving the prescribing practices. An assessment to identify the sustainability of the strategy and its effect within the district healthcare system after the completion of the research phase was undertaken. The study found that peer-group discussion was discontinued in all targeted districts and the improved practices were not sustained after the completion of the research. Various reasons have been found for not continuing the effective intervention.
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Front Oral Health
January 2025
Hospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Objectives: This study aims to examine kindergarten teachers' satisfaction and their perceived impact of an oral health education (OHE) training program.
Methods: This study followed the steps outlined in the Program Evaluation Standards in Public Health recommended by the Centers for Disease Control and Prevention. All kindergarten teachers in Hong Kong were invited to attend the OHE training.
Womens Health Rep (New Rochelle)
January 2025
Department of Psychology & Neuroscience, Baylor University, Waco, Texas, USA.
Background: Hot flashes can be a prevalent issue for postmenopausal women, but traditional treatments such as hormone therapy can have adverse side effects. Recommended psychotherapies for managing hot flashes include cognitive behavioral therapy (CBT) and clinical hypnosis, but an in-depth review comparing the efficacy of both treatments is warranted.
Objectives: The aim of the present scoping review was to assess the clinical significance and efficacy of symptom reduction of CBT and clinical hypnosis as treatments of hot flashes.
Front Public Health
January 2025
Public Health Laboratory Strengthening Unit, WHO Lyon Office, Health Emergencies Programme, World Health Organization, Lyon, France.
Laboratories play a central role in managing public health emergencies. The COVID-19 pandemic imposed unique challenges on global laboratory systems, including testing protocol uncertainties, supply shortages, rapid need for information dissemination, and disruptions to traditional training methods. In response, the WHO established the Public Health Laboratories (PHL) knowledge sharing webinar series whose goals were to respond to the increased demand in up-to-date and reliable information, which WHO is in a unique position to provide.
View Article and Find Full Text PDFFront Mol Neurosci
January 2025
Neuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.
Introduction: The neuron-specific K-Cl cotransporter KCC2 maintains low intracellular chloride levels, which are crucial for fast GABAergic and glycinergic neurotransmission. KCC2 also plays a pivotal role in the development of excitatory glutamatergic neurotransmission by promoting dendritic spine maturation. The cytoplasmic C-terminal domain (KCC2-CTD) plays a critical regulatory role in the molecular mechanisms controlling the cotransporter activity through dimerization, phosphorylation, and protein interaction.
View Article and Find Full Text PDFFront Psychol
January 2025
Department of Educational Psychology, University of Georgia, Athens, GA, United States.
Introduction: Diagnostic classification models (DCMs) have received increasing attention in cross-sectional studies. However, L2 learning studies, tracking skill development over time, require models suited for longitudinal analyses. Growth DCMs offer a promising framework for such analyses.
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