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A Rare Pediatric Giant Cell Tumor of the Clivus Bone, H3.3 p.Gly35Trp-mutated: Case Report and Mini-review of the Literature.
Turk Arch Pediatr
January 2025
Pathology Unit, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Introduction: Giant cell tumor of bone (GCTB) is a rare, typically benign neoplasm that primarily affects long bones in adults, with clival involvement being extremely rare, particularly in pediatric cases: a mini-review shows a total of 28 described cases, of which only 5 were truly pediatric (within 14 years of age). Surgery is the treatment of choice, and Denosumab is reported to be the most effective drug therapy. To date, the GCTB's molecular hallmark is the somatic mutation p.
View Article and Find Full Text PDFUnusual post-blepharoplasty infection: case study.
Dermatol Reports
September 2024
Associate Clinical Professor, Department of Surgery, UGA/UA Medical Partnership, Athens, Georgia.
Post-procedure infections following in-office blepharoplasty are rare. is a weakly acid-fast, gram-positive, aerobic Actinomyces that rarely causes infections in humans. A 35-year-old female presented two weeks after an upper blepharoplasty with cyst-like swellings near the incision site.
View Article and Find Full Text PDFIntracavernous Aneurysm Mimicking Tolosa-Hunt Syndrome.
Maedica (Bucur)
September 2024
Professor, 1st Academic ORL Department, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Introduction: Tolosa-Hunt syndrome (THS) is a disorder related to inflammation of cavernous sinus and superior orbital fissure that usually presents with ophthalmoplegia and oculomotor nerve palsies. The etiology of the syndrome is unknown and the diagnosis is set by exclusion of other clinical conditions that manifest in a similar way. Intracranial aneurysms, such as intracavernous ones, should be included in the differential diagnosis as they can compress cranial nerves leading to similar clinical presentation.
View Article and Find Full Text PDF"At the end of the tunnel": Endonasal endoscopy for a giant GH secreting pituitary tumor with conchal dysplastic sphenoid in McCune-Albright syndrome.
J Clin Neurosci
December 2024
Dept. of Neurosurgery, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Identifying prognostic predictors for postoperative pituitary neuroendocrine tumour recurrence: an integrated clinical, radiological, and immunohistochemistry assessment.
Br J Neurosurg
August 2024
Department of Neurosurgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan (R.O.C.).
Objective: Pituitary neuroendocrine tumours (PitNETs) are the second most common type of intracranial tumour. Several studies have explored the prognostic factors for PitNETs. However, prognostic factors for postoperative PitNET recurrence remain not fully understood.
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