Nine Staphylococcus capitis isolates from blood cultures of newborns were examined for resistance to vancomycin. MICs were within the susceptible range, but population profiling revealed a resistant subpopulation. Only isolates with the largest subpopulation were identified as heteroresistant to vancomycin by Etest. This finding may have therapeutic implications.
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http://dx.doi.org/10.1128/JCM.00592-08 | DOI Listing |
Microb Genom
January 2025
Department of Microbiology, Oxford University Hospitals, Oxford, UK.
The NRCS-A strain has emerged as a global cause of late-onset sepsis associated with outbreaks in neonatal intensive care units (NICUs) whose transmission is incompletely understood. Demographic and clinical data for 45 neonates with and 90 with other coagulase-negative staphylococci (CoNS) isolated from sterile sites were reviewed, and clinical significance was determined. isolated from 27 neonates at 2 hospitals between 2017 and 2022 underwent long-read (ONT) (=27) and short-read (Illumina) sequencing (=18).
View Article and Find Full Text PDFMicroorganisms
December 2024
Laboratory for Skin Research, Institute for Medical Research, Galilee Medical Center, Nahariya 2210001, Israel.
Facultatively anaerobic spp. and anaerobic spp. are among the most prominent bacteria on human skin.
View Article and Find Full Text PDFMicrobiome Res Rep
August 2024
Department of Bioscience Engineering, University of Antwerp, Antwerpen 2020, Belgium.
The human skin microbiome plays an essential role in protecting against pathogens and other external substances. This open ecosystem is also influenced by personal and environmental factors, but the precise impact of these factors, such as lifestyle and season, is understudied. We focused here on the inner elbow, a skin site prone to inflammatory conditions like atopic dermatitis and psoriasis.
View Article and Find Full Text PDFAppl Environ Microbiol
December 2024
Institute of Biomedicine, Department of Infectious Diseases,The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Unlabelled: Coagulase-negative staphylococci (CoNS) comprise about 50 species, some of which cause septicemia in preterm neonates. CoNS establish early on the skin and in the oral and gut microbiota, from where they may spread to the bloodstream. The colonization pattern preceding septicemia is not well-defined.
View Article and Find Full Text PDFJACC Case Rep
November 2024
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
A 72-year-old man with a history of aortic valve replacement (AVR), mitral valve (MV) repair, and recent valve-in-valve transcatheter aortic valve replacement (TAVR) presented with bacteremia. Computed tomography (CT) and fluorodeoxyglucose positron emission tomography (F-FDG PET) imaging noted a pseudoaneurysm, and he successfully underwent TAVR explant with aortic root and valve replacement.
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