Plasmid analysis of 46 strains of Shigella species confirmed the view about heterogeneity and variability of plasmids composition in these microorganisms. On the other hand,the presence of low-molecular, multiplicated extrachromosomal replicons, which were stable, was shown. Using them, it was possible to divide the Shigella isolates into two major plasmidovars, characterize them according to repertoire of the most stable plasmids and determine epidemically significant variants during sporadic and outbreak incidence of shigellosis in towns Nizhny Novgorod and Kstovo (Nizhny Novgorod region).

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