Stage T2 prostate cancer presented with high serum prostate specific antigen and nonspecific bone lesions.

Objective: To present the case of T2 prostate cancer (PCa) mimicking disseminated PCa that was successfully treated with radical retropubic prostatectomy (RRP). PATIENT AND THE METHOD: The patient had prostate specific antigen (PSA) level higher than 30 ng/ml and multiple atypical lesions on bone scan. TRUS-guided biopsy proved small PCa, only in 1/18 biopsy cores, with Gleason grade 6 (3+3). Bone lesions appeared to be posttraumatic.

Result: The patient underwent RRP; six months after surgery there is no evidence of the disease.

Conclusion: Serum PSA level is the sum of cancer activity, normal and BHP tissue production, as well as the result of other pathological conditions, like prostatitis. In some cases, inflammation can be responsible for high PSA level and over-staging.